Intervention
Intermittent fasting
- Works
- 548
- Clinical trials
- 11
- Total citations
- 52,976
- Open access
- 520
Evidence brief
previewSynthesis (preview — no live AI key for the active provider):
Across the retrieved literature, senescent-cell burden and chronic inflammation recur as central, interacting drivers, with intervention studies reporting functional gains in model organisms. Key works: [1][2][3][4][5].
Publication velocity
19942026
Clinical trials
Prevent Age Resort "Pervaya Liniya" 2025
Open access · US-GOV
First Line Prevent Age Study
Centre Hospitalier Universitaire de Saint Etienne 2025
Open access · US-GOV
Therapeutic Fasting and Immune Aging: A Pilot Study of Tolerance
University of Copenhagen 2025
Open access · US-GOV
FAXAGE: A Randomized, Controlled Clinical Trial Of Fasting And Exercise To Slow Aging In Humans
Oklahoma State University 2023
Open access · US-GOV
Curcumin Supplementation for the Improvement of Diabetes-related Outcomes
University of Oklahoma 2022
Open access · US-GOV
Cerebromicrovascular Effects of Time-Restricted Eating in Older Adults
Ankara Etlik City Hospital 2022
Open access · US-GOV
The Impact of Sarcopenia and CRP-TyG Index (CTI) on Immunotherapy Response in Patients With Metastatic Non-Small Cell Lung Cancer: A Single-Center Retrospective Analysis
Drexel University 2021
Open access · US-GOV
Effects of a 24-week Remote-based Resistance Training Program on Parameters of the Metabolic Syndrome, Cognitive Function, and Quality of Life in Older Adults Living With Mild Cognitive Impairment and Alzheimer's Disease and/or a Related Dementia
University of Genova 2020
Open access · US-GOV
Phase I/II Randomized Clinical Study of Cycles of a New Formulated FMD in Prefrail Elderly.
Most-cited works
Diabetes 2002
Open access · OA
Dysfunction of Mitochondria in Human Skeletal Muscle in Type 2 Diabetes
World Journal of Diabetes 2015
Open access · OA
Oxidative stress, insulin resistance, dyslipidemia and type 2 diabetes mellitus
Ageing Research Reviews 2016
Citation only
Impact of intermittent fasting on health and disease processes
International Journal of Molecular Sciences 2010
Open access · CC-BY
Impact of Dietary Polyphenols on Carbohydrate Metabolism
JAMA 2006
Open access · OA
Effect of 6-Month Calorie Restriction on Biomarkers of Longevity, Metabolic Adaptation, and Oxidative Stress in Overweight Individuals
Trials 2009
Open access · CC-BY
Prevention of non-communicable disease in a population in nutrition transition: Tehran Lipid and Glucose Study phase II
Cell Metabolism 2015
Open access · OA
A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan
Nature Communications 2017
Open access · CC-BY
Caloric restriction improves health and survival of rhesus monkeys
PLoS ONE 2013
Open access · CC-BY
The Age-Specific Quantitative Effects of Metabolic Risk Factors on Cardiovascular Diseases and Diabetes: A Pooled Analysis
Nature Communications 2015
Open access · CC-BY