Evidence brief · intervention
Intermittent fasting
Synthesized from 10 indexed sources ·
2026-06-03 MST
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Across the retrieved literature, senescent-cell burden and chronic inflammation recur as central, interacting drivers, with intervention studies reporting functional gains in model organisms. Key works: [1][2][3][4][5].
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Sources
- [1] A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan
- [2] Interventions to Slow Aging in Humans: Are We Ready?
- [3] The mTOR–Autophagy Axis and the Control of Metabolism
- [4] Intermittent and periodic fasting, longevity and disease
- [5] Fasting as a Therapy in Neurological Disease
- [6] A Ketogenic Diet and the Treatment of Autism Spectrum Disorder
- [7] Human liver epigenetic alterations in non-alcoholic steatohepatitis are related to insulin action
- [8] Fasting: From Physiology to Pathology
- [9] Fasting as Medicine: Mitochondrial and Endothelial Rejuvenation in Vascular Aging.
- [10] Endocrine Adaptations to Prolonged Fasting: From Physiology, Clinical Uncertainties, Translational Challenges to Healthspan Implications.