Intervention
Partial reprogramming (OSK)
- Works
- 721
- Clinical trials
- 14
- Total citations
- 75,393
- Open access
- 651
Evidence brief
previewSynthesis (preview — no live AI key for the active provider):
Across the retrieved literature, senescent-cell burden and chronic inflammation recur as central, interacting drivers, with intervention studies reporting functional gains in model organisms. Key works: [1][2][3][4][5].
Publication velocity
19992026
Clinical trials
Zealand University Hospital 2026
Open access · US-GOV
Deteriorated Metabolic Control in the Perioperative Period in Surgical Patients: What is the Impact of Anesthetic Preparation and Patient Frailty?
Northwestern University 2025
Open access · US-GOV
Emotional Well-being and Biomarkers of Healthy Aging
Seong Hye Choi, MD 2025
Open access · US-GOV
A Multicenter, Feasibility Randomized Controlled Study to Evaluate the Applicability and Safety of the Software 'SUPERAGING' for Cognitive Therapy and Musculoskeletal Analysis in Frail or Prefrail Patients
Seoul National University 2025
Open access · US-GOV
Effects of Lower-Body Electrical Muscle Stimulation Combined With Resistance Training on Body Composition, Muscle Function, and Arteriosclerosis-related Markers in Postmenopausal Women: A Three-arm Randomized Controlled Trial
Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust 2025
Open access · US-GOV
Real-World Long-Term Musculoskeletal and Extra-Skeletal Outcomes of Obesity, Diabetes, Ageing, Frailty, and Sarcopenia: The Oswestry Metabolic BONE Cohort
Odense University Hospital 2024
Open access · US-GOV
Targeting mTOR With Everolimus and/or Physical Training for Preventing Postmenopausal Bone Loss and Accelerated Skeletal Aging: The RapaLoad Study
Universidad Europea de Madrid 2024
Open access · US-GOV
Update on the Detection of Frailty in Older Adults: A Multicenter Cohort Machine Learning-Based Study
Okan University 2021
Open access · US-GOV
The Effect of Frenkel's Stabilization Exercises on Balance, Physical Performance, and Fear of Falling in Geriatric Individuals
Most-cited works
Carcinogenesis 2009
Open access · OA
Epigenetics in cancer
Nature Medicine 2008
Open access · OA
Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production
Cell & Bioscience 2019
Open access · CC-BY
Exosomes: biogenesis, biologic function and clinical potential
British Journal of Pharmacology 2015
Open access · OA
Microglial <scp>M1/M2</scp> polarization and metabolic states
Signal Transduction and Targeted Therapy 2022
Open access · CC-BY
Aging and aging-related diseases: from molecular mechanisms to interventions and treatments
The EMBO Journal 2021
Open access · CC-BY
Autophagy in major human diseases
Endocrine Reviews 2010
Open access · OA
Molecular Aspects of Thyroid Hormone Actions
Physiological Reviews 2002
Preprint · OA
Function and Genetics of Dystrophin and Dystrophin-Related Proteins in Muscle
Journal of Internal Medicine 2020
Open access · CC-BY
Senolytic drugs: from discovery to translation
Journal of Clinical Investigation 2018
Citation only