Intervention
Partial reprogramming (OSK)
- Works
- 93
- Clinical trials
- 10
- Total citations
- 19,078
- Open access
- 84
Evidence brief
previewSynthesis (preview — no live AI key for the active provider):
Across the retrieved literature, senescent-cell burden and chronic inflammation recur as central, interacting drivers, with intervention studies reporting functional gains in model organisms. Key works: [1][2][3][4][5].
Publication velocity
20032026
Clinical trials
Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust 2025
Open access · US-GOV
Real-World Long-Term Musculoskeletal and Extra-Skeletal Outcomes of Obesity, Diabetes, Ageing, Frailty, and Sarcopenia: The Oswestry Metabolic BONE Cohort
Northwestern University 2025
Open access · US-GOV
Emotional Well-being and Biomarkers of Healthy Aging
Seong Hye Choi, MD 2025
Open access · US-GOV
A Multicenter, Feasibility Randomized Controlled Study to Evaluate the Applicability and Safety of the Software 'SUPERAGING' for Cognitive Therapy and Musculoskeletal Analysis in Frail or Prefrail Patients
Odense University Hospital 2024
Open access · US-GOV
Targeting mTOR With Everolimus and/or Physical Training for Preventing Postmenopausal Bone Loss and Accelerated Skeletal Aging: The RapaLoad Study
Okan University 2021
Open access · US-GOV
The Effect of Frenkel's Stabilization Exercises on Balance, Physical Performance, and Fear of Falling in Geriatric Individuals
Purdue University 2020
Open access · US-GOV
Effect of Incorporating Lean Beef Into a Protein-rich Diet During Resistance Training Program on Skeletal Muscle and Connective Tissue Strength and Quality in Older Women
Georgia Institute of Technology 2020
Open access · US-GOV
Optimizing Ankle Exoskeleton Assistance for Walking Across the Life Span
University of Colorado, Denver 2007
Open access · US-GOV
COX Inhibition & Musculoskeletal Responses to Exercise
Most-cited works
Carcinogenesis 2009
Open access · OA
Epigenetics in cancer
British Journal of Pharmacology 2015
Open access · OA
Microglial <scp>M1/M2</scp> polarization and metabolic states
Signal Transduction and Targeted Therapy 2022
Open access · CC-BY
Aging and aging-related diseases: from molecular mechanisms to interventions and treatments
The EMBO Journal 2021
Open access · CC-BY
Autophagy in major human diseases
Journal of Clinical Investigation 2018
Citation only
Mechanisms and functions of cellular senescence
Nature 2017
Citation only
Senescence-associated reprogramming promotes cancer stemness
American Journal of Physiology-Cell Physiology 2006
Citation only
Role of cardiolipin alterations in mitochondrial dysfunction and disease
Advanced Drug Delivery Reviews 2020
Open access · CC-BY
Lipids and cancer: Emerging roles in pathogenesis, diagnosis and therapeutic intervention
Signal Transduction and Targeted Therapy 2022
Open access · CC-BY
Epigenetic regulation of aging: implications for interventions of aging and diseases
Genes & Development 2011
Open access · OA