Intervention
Gene therapy
- Works
- 20
- Clinical trials
- 1
- Total citations
- 2,746
- Open access
- 19
Evidence brief
previewSynthesis (preview — no live AI key for the active provider):
Across the retrieved literature, senescent-cell burden and chronic inflammation recur as central, interacting drivers, with intervention studies reporting functional gains in model organisms. Key works: [1][2][3][4][5].
Publication velocity
20062026
Clinical trials
Unlimited Biotechnology LLC 2026
Open access · US-GOV
CALM-AF-AI: Counteracting Age-related Loss of Muscle With AAV-Follistatin Combined With Angiogenesis-Inducing VEGF Plasmid Gene Therapy
Most-cited works
Signal Transduction and Targeted Therapy 2023
Open access · CC-BY
Endoplasmic reticulum stress: molecular mechanism and therapeutic targets
EMBO Molecular Medicine 2012
Open access · OA
Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer
Annual Review of Medicine 2015
Open access · OA
Lysosomal Storage Diseases: From Pathophysiology to Therapy
Molecular Neurodegeneration 2019
Open access · CC-BY
Glucocerebrosidase and its relevance to Parkinson disease
Proceedings of the National Academy of Sciences 2014
Open access · OA
Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1
Molecular Psychiatry 2020
Open access · CC-BY
Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain
Clinical Cancer Research 2006
Citation only
Aberrant Methylation and Deacetylation of <i>Deleted in Liver Cancer-1</i> Gene in Prostate Cancer: Potential Clinical Applications
Biomaterials Research 2023
Open access · CC-BY
CRISPR/Cas9 assisted stem cell therapy in Parkinson's disease
Biology of the Cell 2019
Preprint · CC-BY
Targeting of the unfolded protein response (UPR) as therapy for Parkinson's disease
Molecular Therapy — Nucleic Acids 2019
Open access · CC-BY