Intervention
Gene therapy
- Works
- 125
- Clinical trials
- 1
- Total citations
- 14,913
- Open access
- 112
Evidence brief
previewSynthesis (preview — no live AI key for the active provider):
Across the retrieved literature, senescent-cell burden and chronic inflammation recur as central, interacting drivers, with intervention studies reporting functional gains in model organisms. Key works: [1][2][3][4][5].
Publication velocity
19992026
Clinical trials
Unlimited Biotechnology LLC 2026
Open access · US-GOV
CALM-AF-AI: Counteracting Age-related Loss of Muscle With AAV-Follistatin Combined With Angiogenesis-Inducing VEGF Plasmid Gene Therapy
Most-cited works
Cell 2014
Open access · CC-BY
Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver
Blood 2001
Open access · OA
Identification of mesenchymal stem/progenitor cells in human first-trimester fetal blood, liver, and bone marrow
Signal Transduction and Targeted Therapy 2022
Open access · CC-BY
Stem cell-based therapy for human diseases
Signal Transduction and Targeted Therapy 2023
Open access · CC-BY
Endoplasmic reticulum stress: molecular mechanism and therapeutic targets
BMC Cell Biology 2006
Open access · CC-BY
Aging of mesenchymal stem cell in vitro
Stem Cells 2005
Open access · OA
Characterization of the Optimal Culture Conditions for Clinical Scale Production of Human Mesenchymal Stem Cells
EMBO Molecular Medicine 2012
Open access · OA
Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer
Journal of Biological Chemistry 1999
Open access · CC-BY
Human Endothelial Cell Life Extension by Telomerase Expression
Molecular Cancer 2022
Open access · CC-BY
Current applications and future perspective of CRISPR/Cas9 gene editing in cancer
Clinical Cancer Research 2007
Citation only