Intervention
Stem-cell therapy
- Works
- 30
- Clinical trials
- 1
- Total citations
- 6,403
- Open access
- 27
Evidence brief
previewSynthesis (preview — no live AI key for the active provider):
Across the retrieved literature, senescent-cell burden and chronic inflammation recur as central, interacting drivers, with intervention studies reporting functional gains in model organisms. Key works: [1][2][3][4][5].
Publication velocity
20032026
Clinical trials
University of Aberdeen 2026
Open access · US-GOV
Regenerative Effects of Young Immortalized and Engineered MSC-Derived EVs on Aging and Senescent Brain Models
Most-cited works
Signal Transduction and Targeted Therapy 2022
Open access · CC-BY
Aging and aging-related diseases: from molecular mechanisms to interventions and treatments
PLoS ONE 2008
Open access · CC-BY
Replicative Senescence of Mesenchymal Stem Cells: A Continuous and Organized Process
Signal Transduction and Targeted Therapy 2023
Open access · CC-BY
Endoplasmic reticulum stress: molecular mechanism and therapeutic targets
Cells 2020
Open access · CC-BY
Mesenchymal Stem/Stromal Cell-Derived Exosomes for Immunomodulatory Therapeutics and Skin Regeneration
Annual Review of Medicine 2015
Open access · OA
Lysosomal Storage Diseases: From Pathophysiology to Therapy
Stem Cells International 2017
Open access · CC-BY
Stemness in Cancer: Stem Cells, Cancer Stem Cells, and Their Microenvironment
Stem Cells International 2016
Open access · CC-BY
Ultraviolet Radiation‐Induced Skin Aging: The Role of DNA Damage and Oxidative Stress in Epidermal Stem Cell Damage Mediated Skin Aging
Cell Death and Disease 2013
Open access · CC-BY
Insulin-like growth factor binding proteins 4 and 7 released by senescent cells promote premature senescence in mesenchymal stem cells
Trends in Cell Biology 2019
Citation only
Epigenetic Regulation of Mesenchymal Stem Cell Homeostasis
Pharmacological Research 2023
Open access · CC-BY