Intervention
Telomerase activation
- Works
- 51
- Clinical trials
- 1
- Total citations
- 7,608
- Open access
- 45
Evidence brief
previewSynthesis (preview — no live AI key for the active provider):
Across the retrieved literature, senescent-cell burden and chronic inflammation recur as central, interacting drivers, with intervention studies reporting functional gains in model organisms. Key works: [1][2][3][4][5].
Publication velocity
19922025
Clinical trials
Universidade Federal de Goias 2020
Open access · US-GOV
Metabolic, Cardiovascular and Psychological Responses to Active Video Game in Older Adults
Most-cited works
New Phytologist 2000
Open access · OA
Building roots in a changing environment: implications for root longevity
New England Journal of Medicine 2005
Open access · OA
Mutations in <i>TERT,</i> the Gene for Telomerase Reverse Transcriptase, in Aplastic Anemia
Genome Medicine 2016
Open access · CC-BY
Roles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapies
EMBO Molecular Medicine 2012
Open access · OA
Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer
Journal of Cell Science 2004
Open access · CC0
Chronic oxidative stress compromises telomere integrity and accelerates the onset of senescence in human endothelial cells
Antioxidants 2020
Open access · CC-BY
Mitochondrial Dysfunction, Oxidative Stress, and Neuroinflammation: Intertwined Roads to Neurodegeneration
Blood 2009
Open access · OA
Sex hormones, acting on the TERT gene, increase telomerase activity in human primary hematopoietic cells
Journal of Alzheimer s Disease 2015
Open access · OA
Mechanisms of Molecular Mimicry Involving the Microbiota in Neurodegeneration
Carcinogenesis 2010
Open access · CC-BY
Stearoyl-CoA desaturase-1: a novel key player in the mechanisms of cell proliferation, programmed cell death and transformation to cancer
PLoS Genetics 2012
Open access · CC-BY