Evidence brief · intervention
Partial reprogramming (OSK)
Synthesized from 10 indexed sources ·
2026-07-26 MST
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Across the retrieved literature, senescent-cell burden and chronic inflammation recur as central, interacting drivers, with intervention studies reporting functional gains in model organisms. Key works: [1][2][3][4][5].
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Sources
- [1] Epigenetics in cancer
- [2] Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production
- [3] Exosomes: biogenesis, biologic function and clinical potential
- [4] Microglial <scp>M1/M2</scp> polarization and metabolic states
- [5] Aging and aging-related diseases: from molecular mechanisms to interventions and treatments
- [6] Autophagy in major human diseases
- [7] Molecular Aspects of Thyroid Hormone Actions
- [8] Function and Genetics of Dystrophin and Dystrophin-Related Proteins in Muscle
- [9] Stem cell dysfunction and rejuvenation strategies in ageing: emerging advances in regenerative medicine.
- [10] Aryl hydrocarbon receptor signaling in osteosarcopenia: an integrative framework for musculoskeletal aging.