Intervention
Plasma dilution / young plasma
- Works
- 139
- Clinical trials
- 4
- Total citations
- 4,679
- Open access
- 127
Evidence brief
previewSynthesis (preview — no live AI key for the active provider):
Across the retrieved literature, senescent-cell burden and chronic inflammation recur as central, interacting drivers, with intervention studies reporting functional gains in model organisms. Key works: [1][2][3][4][5].
Publication velocity
19992026
Clinical trials
Charles University, Czech Republic 2021
Open access · US-GOV
Studie Vlivu darování krevní Plazmy - Plasmapheresis. Study of the Plasma Donation Effect - Plasmapheresis
Neurological Associates of West Los Angeles 2021
Open access · US-GOV
Open Label Study for the Use of Plasmapheresis for Treatment of Age-Related Frailty
Wake Forest University Health Sciences 2020
Open access · US-GOV
A Small-Scale Study to Explore the Safety and Feasibility of Allogeneic Young Plasma Infusion in Older Adults Experiencing Disability Across the Spectrum of Frailty Syndrome
Chandra Duggirala 2018
Open access · US-GOV
Reversing Epigenetic & Other Markers of Senescence by Transfusing Young Plasma To Older Human Subjects
Most-cited works
Science 2014
Preprint · OA
Restoring Systemic GDF11 Levels Reverses Age-Related Dysfunction in Mouse Skeletal Muscle
Cell Cycle 2012
Open access · OA
Heterochronic parabiosis for the study of the effects of aging on stem cells and their niches
The Journal of Experimental Medicine 2018
Open access · OA
A common transcriptomic program acquired in the thymus defines tissue residency of MAIT and NKT subsets
Cell Reports 2018
Open access · CC-BY
Tet2 Rescues Age-Related Regenerative Decline and Enhances Cognitive Function in the Adult Mouse Brain
Nature Aging 2022
Open access · CC-BY
Cell-type-specific aging clocks to quantify aging and rejuvenation in neurogenic regions of the brain
Cell stem cell 2022
Open access · OA
Heterochronic parabiosis induces stem cell revitalization and systemic rejuvenation across aged tissues
Skeletal Muscle 2015
Open access · CC-BY
The ins and outs of muscle stem cell aging
FEBS Journal 2016
Open access · OA
Regulatory T cells and skeletal muscle regeneration
Nature Communications 2018
Open access · CC-BY
Macrophage cells secrete factors including LRP1 that orchestrate the rejuvenation of bone repair in mice
Aging 2020
Open access · CC-BY