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Sirtfoods: New Concept Foods, Functions, and Mechanisms

Otobong Donald Akan, Dandan Qin, Tianyi Guo, Qinlu Lin, Feijun Luo

Foods · 2022 · ▲ 21 citations

Deregulated nutrient-sensing Chronic inflammation Disabled macroautophagy Caloric restriction

Abstract

Sirtfood is a new concept food that compounds diets that can target sirtuins (SIRTs). SIRTs are nicotinamide adenine dinucleotide (NAD+)-dependent deacylases and ADP-ribosyltransferases (enzymes). SIRTs are mediators of calorie restriction (CR) and their activation can achieve some effects similar to CR. SIRTs play essential roles in ameliorating obesity and age-related metabolic diseases. Food ingredients such as resveratrol, piceatannol, anthocyanidin, and quinine are potential modulators of SIRTs. SIRT modulators are involved in autophagy, apoptosis, aging, inflammation, and energy homeostasis. Sirtfood proponents believe that natural Sirtfood recipes exert significant health effects.

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Provenance

Source: OpenAlex
DOI: 10.3390/foods11192955
Canonical: link ↗
Fetched: 2026-07-06 MST

Cite this

APA

Akan, O.D., Qin, D., Guo, T., Lin, Q., & Luo, F. (2022). Sirtfoods: New Concept Foods, Functions, and Mechanisms. <em>Foods</em>. https://doi.org/10.3390/foods11192955

Vancouver

Akan OD, Qin D, Guo T, Lin Q, Luo F. Sirtfoods: New Concept Foods, Functions, and Mechanisms. Foods. 2022. doi:10.3390/foods11192955.

BibTeX

@article{otobong2022Sirtfo, title = {Sirtfoods: New Concept Foods, Functions, and Mechanisms}, author = {Otobong Donald Akan and Dandan Qin and Tianyi Guo and Qinlu Lin and Feijun Luo}, journal = {Foods}, year = {2022}, doi = {10.3390/foods11192955}, }