Longevity intervention
Plasma dilution / young plasma
- Works
- 4
- Most cited
- 2
Most-cited works
Sex-specific longitudinal reversal of aging in old frail mice.
Important studies report acute rejuvenation of mammalian cells and tissues by blood heterochronicity, old plasma dilution, defined factors, and partial reprogramming. And extension of rodent lifespan via single-prong methods was tried in re...
Microvascular Health as a Key Determinant of Organismal Aging.
Aging is a complex, multifaceted process affecting all organ systems, with vascular aging playing a central role in organismal health decline. Beyond its role in circulation, the vascular system acts as a dynamic interface between tissues,...
Reversing Epigenetic & Other Markers of Senescence by Transfusing Young Plasma To Older Human Subjects
This trial is designed to study the effects of monthly transfusions of young healthy male donor plasma on biological age as assessed by DNA methylation levels, and changes in cognitive, renal, and pulmonary function, muscle strength, telome...
Turning back time: effects of young plasma on pan epigenetic clocks and implications for the heart
Narrowing down the mechanisms behind how treating an old animal with EVs from a young animal can turn back time on epigenetic clocks may provide novel targets that can modulate biological aging and improve health and lifespan.