Wrist Circumference in Relation to the Risk of Metabolic Syndrome in Middle-Aged and Elderly Chinese Patients with Type 2 Diabetes

Objective: In this study, we aimed to determine whether wrist circumference is associated with increased with of metabolic syndrome (MetS) among middle-aged and elderly Chinese type 2 diabetes (T2DM) subjects.Method: A total of 470 type 2 diabetes hospitalized patients were included in the study.Data on demographic characteristics, anthropometry and variables were collected.Serum lipid profile, HbA1c, and beta-cell function were detected in blood samples.The diagnosis of MetS was ascertained by the International Diabetes Federation (IDF) criteria.Results: The mean of wrist circumference in male and female patients were 15.5 and 17.0cm, respectively.Weight, body mass index, waist circumference, triglycerides and incident MetS gradually increased with the increment of wrist circumferenc etertiles and HDL gradually decreased with the increment of wrist circumference tertiles (all P<0.05) even after adjustment of onset age of diabetes and duration of T2DM in both gender.When adjusted for body mass index, and waist circumference, the association between wrist circumference and MetS remained significant only among the normal group women (BMI<25kg/m 2 ).Conclusion: These results suggested that a higher wrist circumference was associated with higher risk for MetS in T2DM subjects, especially in the female T2DM with BMI<25kg/m 2 .