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Sesn2 Serves as a Regulator between Mitochondrial Unfolded Protein Response and Mitophagy in Intervertebral Disc Degeneration

Wenning Xu, Chun Liu, Huo‐Liang Zheng, Haixia Xu, Runze Yang, Sheng‐Dan Jiang, Li-xin Zhu

International Journal of Biological Sciences · 2023 · ▲ 29 citations

Loss of proteostasis Mitochondrial dysfunction Disabled macroautophagy

Abstract

could attenuate IVDD by upregulation of Sesn2-induced mitophagy. This study will help to further reveal the mechanism of Sesn2 regulating mitophagy, and open up new ideas for the prevention and treatment of IVDD.

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Provenance

Source: OpenAlex
DOI: 10.7150/ijbs.70211
Canonical: link ↗
Fetched: 2026-06-26 MST

Cite this

APA

Xu, W., Liu, C., Zheng, H., Xu, H., Yang, R., Jiang, S., & Zhu, L. (2023). Sesn2 Serves as a Regulator between Mitochondrial Unfolded Protein Response and Mitophagy in Intervertebral Disc Degeneration. <em>International Journal of Biological Sciences</em>. https://doi.org/10.7150/ijbs.70211

Vancouver

Xu W, Liu C, Zheng H, Xu H, Yang R, Jiang S, et al. Sesn2 Serves as a Regulator between Mitochondrial Unfolded Protein Response and Mitophagy in Intervertebral Disc Degeneration. International Journal of Biological Sciences. 2023. doi:10.7150/ijbs.70211.

BibTeX

@article{wenning2023SesnSe, title = {Sesn2 Serves as a Regulator between Mitochondrial Unfolded Protein Response and Mitophagy in Intervertebral Disc Degeneration}, author = {Wenning Xu and Chun Liu and Huo‐Liang Zheng and Haixia Xu and Runze Yang and Sheng‐Dan Jiang and Li-xin Zhu}, journal = {International Journal of Biological Sciences}, year = {2023}, doi = {10.7150/ijbs.70211}, }