Hallmark of aging · H04
Loss of proteostasis
Decline in protein quality control.
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Most-cited works
Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010
The IntCal20 Northern Hemisphere Radiocarbon Age Calibration Curve (0–55 cal kBP)
ABSTRACT Radiocarbon ( 14 C) ages cannot provide absolutely dated chronologies for archaeological or paleoenvironmental studies directly but must be converted to calendar age equivalents using a calibration curve compensating for fluctuatio...
SCENIC: single-cell regulatory network inference and clustering
Dictionary learning for integrative, multimodal and scalable single-cell analysis
Coming of age: ten years of next-generation sequencing technologies
Head and neck squamous cell carcinoma
Most head and neck cancers are derived from the mucosal epithelium in the oral cavity, pharynx and larynx and are known collectively as head and neck squamous cell carcinoma (HNSCC). Oral cavity and larynx cancers are generally associated w...
Intcal04 Terrestrial Radiocarbon Age Calibration, 0–26 Cal Kyr BP
A new calibration curve for the conversion of radiocarbon ages to calibrated (cal) ages has been constructed and internationally ratified to replace IntCal98, which extended from 0–24 cal kyr BP (Before Present, 0 cal BP = AD 1950). The new...
Parkinson's disease
The golden age: gold nanoparticles for biomedicine
Gold nanoparticles have been used in biomedical applications since their first colloidal syntheses more than three centuries ago. However, over the past two decades, their beautiful colors and unique electronic properties have also attracte...