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Rapamycin and Alzheimer disease: a hypothesis for the effective use of rapamycin for treatment of neurodegenerative disease

Autophagy · 2023 · ▲ 42 citations

Deregulated nutrient-sensing Rapamycin / mTOR inhibition

Abstract

AD: Alzheimer disease; APP: amyloid beta precursor protein; MAPT/tau: microtubule associated protein tau; MTOR: mechanistic target of rapamycin kinase; MTORC1: mechanistic target of rapamycin kinase complex 1.

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Provenance

Source: OpenAlex
DOI: 10.1080/15548627.2023.2175569
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Fetched: 2026-06-13 MST

Cite this

APA

Carosi, J.M., & Sargeant, T.J. (2023). Rapamycin and Alzheimer disease: a hypothesis for the effective use of rapamycin for treatment of neurodegenerative disease. <em>Autophagy</em>. https://doi.org/10.1080/15548627.2023.2175569

Vancouver

Carosi JM, Sargeant TJ. Rapamycin and Alzheimer disease: a hypothesis for the effective use of rapamycin for treatment of neurodegenerative disease. Autophagy. 2023. doi:10.1080/15548627.2023.2175569.

BibTeX

@unpublished{julian2023Rapamy, title = {Rapamycin and Alzheimer disease: a hypothesis for the effective use of rapamycin for treatment of neurodegenerative disease}, author = {Julian M. Carosi and Timothy J. Sargeant}, journal = {Autophagy}, year = {2023}, doi = {10.1080/15548627.2023.2175569}, }