Open access · OA
via OpenAlex
Metformin improves healthspan and lifespan in mice
Alejandro Martín‐Montalvo, Evi M. Mercken, Sarah Jayne Mitchell, Hector H. Palacios, Patricia L. Mote, Morten Scheibye‐Knudsen, Ana P. Gomes, Theresa M. Ward, Robin K. Minor, Marie‐José Blouin, Matthias Georg Schwab, Michaël Pollak, Yongqing Zhang, Yinbing Yu, Kevin G. Becker
Nature Communications · 2013 · ▲ 1,480 citations
Abstract
A 2013 study in Nature Communications demonstrates that treating mice with low-dose metformin significantly improves their healthspan(definition) and lifespan.
◌ CITATION ONLY
Full text is not openly licensed for redistribution here. Read it at the source:
Provenance
- Source
- OpenAlex
- DOI
- 10.1038/ncomms3192
- Canonical
- link ↗
- Fetched
- 2026-09-28 MST
Cite this
APA
Martín‐Montalvo, A., Mercken, E.M., Mitchell, S.J., Palacios, H.H., Mote, P.L., Scheibye‐Knudsen, M., Gomes, A.P., Ward, T.M., Minor, R.K., Blouin, M., Schwab, M.G., Pollak, M., Zhang, Y., Yu, Y., Becker, K.G., Bohr, V.A., Ingram, D.K., Sinclair, D.A., Wolf, N.S., & Spindler, S.R. (2013). Metformin improves healthspan and lifespan in mice. <em>Nature Communications</em>. https://doi.org/10.1038/ncomms3192
Vancouver
Martín‐Montalvo A, Mercken EM, Mitchell SJ, Palacios HH, Mote PL, Scheibye‐Knudsen M, et al. Metformin improves healthspan and lifespan in mice. Nature Communications. 2013. doi:10.1038/ncomms3192.
BibTeX
@article{alejandro2013Metfor,
title = {Metformin improves healthspan and lifespan in mice},
author = {Alejandro Martín‐Montalvo and Evi M. Mercken and Sarah Jayne Mitchell and Hector H. Palacios and Patricia L. Mote and Morten Scheibye‐Knudsen and Ana P. Gomes and Theresa M. Ward and Robin K. Minor and Marie‐José Blouin and Matthias Georg Schwab and Michaël Pollak and Yongqing Zhang and Yinbing Yu and Kevin G. Becker and Vilhelm A. Bohr and Donald K. Ingram and David A. Sinclair and Norman S. Wolf and Stephen R. Spindler and Michel Bernier and Rafael de Cabo},
journal = {Nature Communications},
year = {2013},
doi = {10.1038/ncomms3192},
}
Research neighborhood
References, citing works, and semantically nearest findings. Click a node to open it.
Related findings
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature 2013
Preprint
Faculty Opinions recommendation of Metformin improves healthspan and lifespan in mice.
Cell Metabolism 2018
Open access · OA
Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice
Nature 2012
Citation only
The sirtuin SIRT6 regulates lifespan in male mice
Nature 2023
Preprint · OA
Increased hyaluronan by naked mole-rat Has2 improves healthspan in mice
Nature Aging 2022
Citation only
Healthspan versus lifespan: new medicines to close the gap
SSRN Electronic Journal 2022
Preprint · OA