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Deacetylation of ATG7 drives the induction of macroautophagy and LC3-associated microautophagy

Yinfeng Xu, Chuying Qian, Qian Wang, Lijiang Song, Zhengfu He, Wei Liu, Wei Wan

Autophagy · 2023 · ▲ 21 citations

Disabled macroautophagy Deregulated nutrient-sensing Rapamycin / mTOR inhibition Cell culture / in vitro Mouse

Abstract

AMPK: AMP-activated protein kinase; ATG: autophagy-related; cGAMP: cyclic GMP-AMP; CGAS: cyclic GMP-AMP synthase; CREBBP/CBP: CREB binding protein; EGF: epidermal growth factor; EGFR: epidermal growth factor receptor; EP300/p300: E1A binding protein p300; IFNB1: interferon beta 1; ISD: interferon stimulatory DNA; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; MCOLN1/TRPML1: mucolipin TRP cation channel 1; MEF: mouse embryonic fibroblast; MTOR: mechanistic target of rapamycin kinase; NAM: nicotinamide; PE: phosphatidylethanolamine; PTM: post-translational modification; RB1CC1/FIP200: RB1 inducible coiled-coil 1; SIRT: sirtuin; SQSTM1/p62: sequestosome 1; STING1: stimulator of interferon response cGAMP interactor 1; TSA: trichostatin A; ULK1: unc-51 like autophagy activating kinase 1; WIPI2: WD repeat domain, phosphoinositide interacting 2; WT: wild-type.

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Provenance

Source: OpenAlex
DOI: 10.1080/15548627.2023.2287932
Canonical: link ↗
Fetched: 2026-06-05 MST

Cite this

APA

Xu, Y., Qian, C., Wang, Q., Song, L., He, Z., Liu, W., & Wan, W. (2023). Deacetylation of ATG7 drives the induction of macroautophagy and LC3-associated microautophagy. <em>Autophagy</em>. https://doi.org/10.1080/15548627.2023.2287932

Vancouver

Xu Y, Qian C, Wang Q, Song L, He Z, Liu W, et al. Deacetylation of ATG7 drives the induction of macroautophagy and LC3-associated microautophagy. Autophagy. 2023. doi:10.1080/15548627.2023.2287932.

BibTeX

@unpublished{yinfeng2023Deacet, title = {Deacetylation of ATG7 drives the induction of macroautophagy and LC3-associated microautophagy}, author = {Yinfeng Xu and Chuying Qian and Qian Wang and Lijiang Song and Zhengfu He and Wei Liu and Wei Wan}, journal = {Autophagy}, year = {2023}, doi = {10.1080/15548627.2023.2287932}, }