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Evidence brief · intervention

Caloric restriction

Synthesized from 10 indexed sources · 2026-07-27 MST · preview (no AI key)
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Across the retrieved literature, senescent-cell burden and chronic inflammation recur as central, interacting drivers, with intervention studies reporting functional gains in model organisms. Key works: [1][2][3][4][5].

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Sources

  1. [1] The Free Radical Theory of Aging Matures
  2. [2] Oxidative Stress, Caloric Restriction, and Aging
  3. [3] Cancer is a Preventable Disease that Requires Major Lifestyle Changes
  4. [4] Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys
  5. [5] <i>daf-2</i> , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in <i>Caenorhabditis elegans</i>
  6. [6] Sirtuin activators mimic caloric restriction and delay ageing in metazoans
  7. [7] Aging and aging-related diseases: from molecular mechanisms to interventions and treatments
  8. [8] Ink4a/Arf expression is a biomarker of aging
  9. [9] Sexually Dimorphic Response to Dietary Restriction-induced Longevity and Muscle Rejuvenation in <i>Nothobranchius furzeri</i>
  10. [10] Bench to bedside: is rapamycin headed for the docTOR?
All Caloric restriction works → Intervention dossier →