Author
Johan Auwerx
- Indexed works
- 44
- Total citations
- 14,305
- Active years
- 16
Collaborators
Works in the record
Nature Reviews Molecular Cell Biology 2012
Preprint · OA
Sirtuins as regulators of metabolism and healthspan
Cell 2013
Open access · OA
The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling
Nature Medicine 2016
Preprint · OA
Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents
Nature 2013
Preprint · OA
Mitonuclear protein imbalance as a conserved longevity mechanism
Endocrine Reviews 2010
Open access · OA
The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways
The Journal of Cell Biology 2017
Open access · OA
Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals
Nature 2017
Preprint · CC-BY
Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity
Nature Metabolism 2023
Preprint · OA
Mitophagy in human health, ageing and disease
Scientific Reports 2011
Open access · CC-BY
The metabolic footprint of aging in mice
Nature 2018
Preprint · OA
De novo NAD+ synthesis enhances mitochondrial function and improves health
European Heart Journal 2015
Open access · CC-BY
Protective effects of sirtuins in cardiovascular diseases: from bench to bedside
Trends in Molecular Medicine 2021
Open access · CC-BY
Impact of the Natural Compound Urolithin A on Health, Disease, and Aging
Nature Communications 2016
Open access · CC-BY
NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells
Hepatology 2015
Open access · CC-BY
Eliciting the mitochondrial unfolded protein response by nicotinamide adenine dinucleotide repletion reverses fatty liver disease in mice
Cell Metabolism 2014
Open access · CC-BY
NAD+-Dependent Activation of Sirt1 Corrects the Phenotype in a Mouse Model of Mitochondrial Disease
The Annual Review of Pharmacology and Toxicology 2017
Preprint · OA
Repairing Mitochondrial Dysfunction in Disease
Genes & Development 2013
Preprint · OA
Emerging roles of the corepressors NCoR1 and SMRT in homeostasis
Science 2019
Preprint · CC-BY
Mitocellular communication: Shaping health and disease
Cell Reports Medicine 2022
Open access · CC-BY
Urolithin A improves muscle strength, exercise performance, and biomarkers of mitochondrial health in a randomized trial in middle-aged adults
Nature Aging 2022
Open access · OA
Pleiotropic effects of mitochondria in aging
Nature Protocols 2016
Preprint · CC-BY
A screening-based platform for the assessment of cellular respiration in Caenorhabditis elegans
American Journal of Clinical Nutrition 2020
Preprint · OA
Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans
Genes & Development 2015
Preprint · CC-BY
Loss of the RNA polymerase III repressor MAF1 confers obesity resistance
European Journal of Clinical Nutrition 2021
Open access · CC-BY
Direct supplementation with Urolithin A overcomes limitations of dietary exposure and gut microbiome variability in healthy adults to achieve consistent levels across the population
The Journal of Cell Biology 2012
Open access · CC-BY
Exploring the therapeutic space around NAD+
Scientific Reports 2018
Open access · CC-BY
Mitochondrial function is impaired in the skeletal muscle of pre-frail elderly
Cold Spring Harbor Symposia on Quantitative Biology 2011
Preprint · OA
NAD+ as a Signaling Molecule Modulating Metabolism
Nature Communications 2017
Open access · CC-BY
Bayesian association scan reveals loci associated with human lifespan and linked biomarkers
Science 2022
Preprint · OA
Sex- and age-dependent genetics of longevity in a heterogeneous mouse population
Circulation Research 2019
Open access · OA
Fine-Tuning of PGC1α Expression Regulates Cardiac Function and Longevity
Journal of Lipid Research 2019
Open access · CC-BY
Niacin: an old lipid drug in a new NAD+ dress
Experimental Neurology 2020
Open access · CC-BY
Evaluation of the NAD+ biosynthetic pathway in ALS patients and effect of modulating NAD+ levels in hSOD1-linked ALS mouse models
Nature Aging 2023
Preprint · OA
Induction of mitochondrial recycling reverts age-associated decline of the hematopoietic and immune systems
Science Advances 2022
Open access · CC-BY
eNAMPT actions through nucleus accumbens NAD <sup>+</sup> /SIRT1 link increased adiposity with sociability deficits programmed by peripuberty stress
Nature Communications 2022
Open access · CC-BY
The mouse metallomic landscape of aging and metabolism
Nature Aging 2022
Open access · OA
Sphingolipids accumulate in aged muscle, and their reduction counteracts sarcopenia
Cell Research 2026
Open access · CC-BY
Mitophagy in the pathogenesis and management of disease
Brain 2020
Open access · OA
Gene replacement therapy provides benefit in an adult mouse model of Leigh syndrome
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2018
Open access · OA
Genetic cartography of longevity in humans and mice: Current landscape and horizons
The Journal of Clinical Endocrinology & Metabolism 2021
Open access · OA
Nicotinamide Riboside Enhances In Vitro Beta-adrenergic Brown Adipose Tissue Activity in Humans
Innovation in Aging 2017
Open access · OA
ORALLY ADMINISTERED UROLITHIN A IS SAFE AND MODULATES MUSCLE AND MITOCHONDRIAL BIOMARKERS IN ELDERLY
Innovation in Aging 2018
Open access · OA
TRANSLATING UROLITHIN A BENEFITS ON MUSCLE MITOCHONDRIA TO HUMANS
Current Developments in Nutrition 2019
Open access · CC-BY
Urolithin A, a Gut Microbiome Derived Metabolite Improves Mitochondrial and Cellular Health: Results from a Randomized, Placebo-controlled, Double-blind Clinical Trial (FS09-06-19)
bioRxiv (Cold Spring Harbor Laboratory) 2025
Preprint · CC-BY