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The Role of Adipokines in Health and Disease

Vicente Javier Clemente‐Suárez, Laura Redondo-Flórez, Ana Isabel Beltrán-Velasco, Alexandra Martín-Rodríguez, Ismael Martínez‐Guardado, Eduardo Navarro-Jiménez, Carmen Cecilia Laborde-Cárdenas, José Francisco Tornero-Aguilera

Biomedicines · 2023 · ▲ 398 citations

Dysbiosis Altered intercellular communication Chronic inflammation Exercise Review

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Abstract

Adipokines are cell-signaling proteins secreted by adipose tissue that has been related to a low-grade state of inflammation and different pathologies. The present review aims to analyze the role of adipokines in health and disease in order to understand the important functions and effects of these cytokines. For this aim, the present review delves into the type of adipocytes and the cytokines produced, as well as their functions; the relations of adipokines in inflammation and different diseases such as cardiovascular, atherosclerosis, mental diseases, metabolic disorders, cancer, and eating behaviors; and finally, the role of microbiota, nutrition, and physical activity in adipokines is discussed. This information would allow for a better understanding of these important cytokines and their effects on body organisms.

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Provenance

Source: OpenAlex
DOI: 10.3390/biomedicines11051290
Canonical: link ↗
Fetched: 2026-06-06 MST

Cite this

APA

Clemente‐Suárez, V.J., Redondo-Flórez, L., Beltrán-Velasco, A.I., Martín-Rodríguez, A., Martínez‐Guardado, I., Navarro-Jiménez, E., Laborde-Cárdenas, C.C., & Tornero-Aguilera, J.F. (2023). The Role of Adipokines in Health and Disease. <em>Biomedicines</em>. https://doi.org/10.3390/biomedicines11051290

Vancouver

Clemente‐Suárez VJ, Redondo-Flórez L, Beltrán-Velasco AI, Martín-Rodríguez A, Martínez‐Guardado I, Navarro-Jiménez E, et al. The Role of Adipokines in Health and Disease. Biomedicines. 2023. doi:10.3390/biomedicines11051290.

BibTeX

@article{vicente2023TheRol, title = {The Role of Adipokines in Health and Disease}, author = {Vicente Javier Clemente‐Suárez and Laura Redondo-Flórez and Ana Isabel Beltrán-Velasco and Alexandra Martín-Rodríguez and Ismael Martínez‐Guardado and Eduardo Navarro-Jiménez and Carmen Cecilia Laborde-Cárdenas and José Francisco Tornero-Aguilera}, journal = {Biomedicines}, year = {2023}, doi = {10.3390/biomedicines11051290}, }