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The journey of resveratrol from yeast to human

Silvie Timmers, Johan H. Auwerx, Patrick Schrauwen

Aging · 2012 · ▲ 173 citations

Deregulated nutrient-sensing Caloric restriction Yeast Human

Abstract

The natural polyphenolic compound resveratrol was first discovered in the 1940s. In the recent years, this compound received renewed interest as several findings implicated resveratrol as a potent SIRT1 activator capable of mimicking the effects of calorie restriction, and regulating longevity in lower organisms. Given the worldwide increase in age-related metabolic diseases the beneficial effects of resveratrol on metabolism and healthy aging in humans are currently a topic of intense investigation.

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Provenance

Source: OpenAlex
DOI: 10.18632/aging.100445
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Fetched: 2026-09-29 MST

Cite this

APA

Timmers, S., Auwerx, J.H., & Schrauwen, P. (2012). The journey of resveratrol from yeast to human. <em>Aging</em>. https://doi.org/10.18632/aging.100445

Vancouver

Timmers S, Auwerx JH, Schrauwen P. The journey of resveratrol from yeast to human. Aging. 2012. doi:10.18632/aging.100445.

BibTeX

@article{silvie2012Thejou, title = {The journey of resveratrol from yeast to human}, author = {Silvie Timmers and Johan H. Auwerx and Patrick Schrauwen}, journal = {Aging}, year = {2012}, doi = {10.18632/aging.100445}, }