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Sustained Activation of mTORC1 in Skeletal Muscle Inhibits Constitutive and Starvation-Induced Autophagy and Causes a Severe, Late-Onset Myopathy

Perrine Castets, Shuo Lin, Nathalie Rion, Sabrina Di Fulvio, Klaas Romanino, Maitea Guridi, Stephan Frank, Lionel Tintignac, Michael Sinnreich, Markus A. Rüegg

Cell Metabolism · 2013 · ▲ 307 citations

Deregulated nutrient-sensing Disabled macroautophagy

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Provenance

Source: OpenAlex
DOI: 10.1016/j.cmet.2013.03.015
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Fetched: 2026-08-02 MST

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APA

Castets, P., Lin, S., Rion, N., Fulvio, S.D., Romanino, K., Guridi, M., Frank, S., Tintignac, L., Sinnreich, M., & Rüegg, M.A. (2013). Sustained Activation of mTORC1 in Skeletal Muscle Inhibits Constitutive and Starvation-Induced Autophagy and Causes a Severe, Late-Onset Myopathy. <em>Cell Metabolism</em>. https://doi.org/10.1016/j.cmet.2013.03.015

Vancouver

Castets P, Lin S, Rion N, Fulvio SD, Romanino K, Guridi M, et al. Sustained Activation of mTORC1 in Skeletal Muscle Inhibits Constitutive and Starvation-Induced Autophagy and Causes a Severe, Late-Onset Myopathy. Cell Metabolism. 2013. doi:10.1016/j.cmet.2013.03.015.

BibTeX

@article{perrine2013Sustai, title = {Sustained Activation of mTORC1 in Skeletal Muscle Inhibits Constitutive and Starvation-Induced Autophagy and Causes a Severe, Late-Onset Myopathy}, author = {Perrine Castets and Shuo Lin and Nathalie Rion and Sabrina Di Fulvio and Klaas Romanino and Maitea Guridi and Stephan Frank and Lionel Tintignac and Michael Sinnreich and Markus A. Rüegg}, journal = {Cell Metabolism}, year = {2013}, doi = {10.1016/j.cmet.2013.03.015}, }