Open access · OA via OpenAlex

Spermidine reduces cancer-related mortality in humans

Federico Pietrocola, Francesca Castoldi, Oliver Kepp, Didac Carmona‐Gutiérrez, Frank Madeo, Guido Kroemer

Autophagy · 2018 · ▲ 46 citations

Disabled macroautophagy Spermidine Human

Abstract

A recent prospective epidemiological study suggested that an increase in the nutritional uptake of the natural polyamine spermidine is associated with reduced overall and cancer-specific mortality. Here, we speculate through which mechanisms spermidine might exert such oncopreventive effects.Abbreviations: ACLY, ATP citrate lyase; ATG, autophagy-related gene; CoA, coenzyme A; NSCLC, non-small cell lung cancer

◌ CITATION ONLY
Full text is not openly licensed for redistribution here. Read it at the source:

Read at source →

Provenance

Source: OpenAlex
DOI: 10.1080/15548627.2018.1539592
Canonical: link ↗
Fetched: 2026-08-25 MST

Cite this

APA

Pietrocola, F., Castoldi, F., Kepp, O., Carmona‐Gutiérrez, D., Madeo, F., & Kroemer, G. (2018). Spermidine reduces cancer-related mortality in humans. <em>Autophagy</em>. https://doi.org/10.1080/15548627.2018.1539592

Vancouver

Pietrocola F, Castoldi F, Kepp O, Carmona‐Gutiérrez D, Madeo F, Kroemer G. Spermidine reduces cancer-related mortality in humans. Autophagy. 2018. doi:10.1080/15548627.2018.1539592.

BibTeX

@article{federico2018Spermi, title = {Spermidine reduces cancer-related mortality in humans}, author = {Federico Pietrocola and Francesca Castoldi and Oliver Kepp and Didac Carmona‐Gutiérrez and Frank Madeo and Guido Kroemer}, journal = {Autophagy}, year = {2018}, doi = {10.1080/15548627.2018.1539592}, }