S-427 Impact of age at diagnosis of type 2 diabetes on metabolic manifestations of diabetic ketoacidosi

Aim: The aim of this study was to investigate whether there are any differences in the manifestations of diabetic ketoacidosis (DKA) and in recurrence rate of DKA according to an age at diagnosis of type 2 diabetes. Methods: We enrolled 61 type 2 diabetic patients who presented with diabetic ketoacidosis from 2003 to 2015. We obtained clinical, biochemical and recurrence rate data from electronic records. The subjects were divided into two groups based on the age at diagnosis of diabetes: age of diagnosis ≥ 40 years and age of diagnosis ＜40 years. Mean follow-up period was 19.9 months (range 0-118). Results: There were no significant differences of body mass index, glucose levels, triglyceride levels and HbA1c levels between two groups at the presentation of DKA. There was no significant difference in frequency of severe DKA between two groups. In addition, there was no significant difference in recurrence rate of DKA between two groups during the follow-up period. Conclusions: Our results suggest that younger age at diagnosis of type 2 diabetes is not associated with poor metabolic conditions in regards to DKA, compared with usual age at diagnosis of type 2 diabetes.