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Puerarin extends the lifespan of Drosophila melanogaster by activating autophagy

Ai-Wen Kang, Chi Chin Sun, Haitao Li, Kun Zhong, Xuhui Zeng, Zhifeng Gu, Bingqian Li, Xiaoning Zhang, Jianlin Gao, Tianxing Chen

Food & Function · 2023 · ▲ 20 citations

Disabled macroautophagy Drosophila

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Abstract

Puerarin extends longevity of flies by improving climbing activity, ATP production, and stress resistance but repressing fecundity. Puerarin promotes lysosome-involved autophagy via inhibiting TOR phosphorylation, resulting in longevity of flies.

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Provenance

Source: OpenAlex
DOI: 10.1039/d2fo02800j
Canonical: link ↗
Fetched: 2026-10-22 MST

Cite this

APA

Kang, A., Sun, C.C., Li, H., Zhong, K., Zeng, X., Gu, Z., Li, B., Zhang, X., Gao, J., & Chen, T. (2023). Puerarin extends the lifespan of Drosophila melanogaster by activating autophagy. <em>Food & Function</em>. https://doi.org/10.1039/d2fo02800j

Vancouver

Kang A, Sun CC, Li H, Zhong K, Zeng X, Gu Z, et al. Puerarin extends the lifespan of Drosophila melanogaster by activating autophagy. Food & Function. 2023. doi:10.1039/d2fo02800j.

BibTeX

@article{aiwen2023Puerar, title = {Puerarin extends the lifespan of Drosophila melanogaster by activating autophagy}, author = {Ai-Wen Kang and Chi Chin Sun and Haitao Li and Kun Zhong and Xuhui Zeng and Zhifeng Gu and Bingqian Li and Xiaoning Zhang and Jianlin Gao and Tianxing Chen}, journal = {Food & Function}, year = {2023}, doi = {10.1039/d2fo02800j}, }