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Physiologic Effects of Lowering Caloric Intake in Nonhuman Primates and Nonobese Humans

Susan B. Roberts, Xavier Pi‐Sunyer, Lewis H. Kuller, Mark A. Lane, PT Ellison, Jerilynn C. Prior, Sue A. Shapses

The Journals of Gerontology Series A · 2001 · ▲ 50 citations

Dysbiosis Caloric restriction Non-human primate Human Review

Abstract

Caloric restriction (CR) reduces the rate of aging and increases life span in all small animal species studied to date, but the effects of CR in humans remain uncertain. This review summarizes current knowledge of the effects of CR in nonhuman primates and humans. The results suggest that CR has a range of beneficial effects in nonhuman primates studied under laboratory conditions, and short-term markers of CR seen in animal models appear to occur in humans subject to CR also. However, the overall benefit of CR in human populations remains to be established, and studies in human populations are needed.

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Provenance

Source: OpenAlex
DOI: 10.1093/gerona/56.suppl_1.66
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Fetched: 2026-07-15 MST

Cite this

APA

Roberts, S.B., Pi‐Sunyer, X., Kuller, L.H., Lane, M.A., Ellison, P., Prior, J.C., & Shapses, S.A. (2001). Physiologic Effects of Lowering Caloric Intake in Nonhuman Primates and Nonobese Humans. <em>The Journals of Gerontology Series A</em>. https://doi.org/10.1093/gerona/56.suppl_1.66

Vancouver

Roberts SB, Pi‐Sunyer X, Kuller LH, Lane MA, Ellison P, Prior JC, et al. Physiologic Effects of Lowering Caloric Intake in Nonhuman Primates and Nonobese Humans. The Journals of Gerontology Series A. 2001. doi:10.1093/gerona/56.suppl_1.66.

BibTeX

@article{susan2001Physio, title = {Physiologic Effects of Lowering Caloric Intake in Nonhuman Primates and Nonobese Humans}, author = {Susan B. Roberts and Xavier Pi‐Sunyer and Lewis H. Kuller and Mark A. Lane and PT Ellison and Jerilynn C. Prior and Sue A. Shapses}, journal = {The Journals of Gerontology Series A}, year = {2001}, doi = {10.1093/gerona/56.suppl_1.66}, }