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Pan-mTOR inhibitors sensitize the senolytic activity of navitoclax via mTORC2 inhibition-mediated apoptotic signaling
Weitong Xu, Tingting Zhao, Honghan Chen, Ning Huang, Hui Gong, Jian Zhang, Yang Yu, Tiepeng Li, Gongchang Zhang, Chuhui Gong, Ming Yang, Hengyi Xiao
Biochemical Pharmacology · 2022 · ▲ 16 citations
Deregulated nutrient-sensing
Cellular senescence
Altered intercellular communication
Rapamycin / mTOR inhibition
Senolytics
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- 10.1016/j.bcp.2022.115045
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- 2026-06-13 MST
Cite this
APA
Xu, W., Zhao, T., Chen, H., Huang, N., Gong, H., Zhang, J., Yu, Y., Li, T., Zhang, G., Gong, C., Yang, M., & Xiao, H. (2022). Pan-mTOR inhibitors sensitize the senolytic activity of navitoclax via mTORC2 inhibition-mediated apoptotic signaling. <em>Biochemical Pharmacology</em>. https://doi.org/10.1016/j.bcp.2022.115045
Vancouver
Xu W, Zhao T, Chen H, Huang N, Gong H, Zhang J, et al. Pan-mTOR inhibitors sensitize the senolytic activity of navitoclax via mTORC2 inhibition-mediated apoptotic signaling. Biochemical Pharmacology. 2022. doi:10.1016/j.bcp.2022.115045.
BibTeX
@article{weitong2022PanmTO,
title = {Pan-mTOR inhibitors sensitize the senolytic activity of navitoclax via mTORC2 inhibition-mediated apoptotic signaling},
author = {Weitong Xu and Tingting Zhao and Honghan Chen and Ning Huang and Hui Gong and Jian Zhang and Yang Yu and Tiepeng Li and Gongchang Zhang and Chuhui Gong and Ming Yang and Hengyi Xiao},
journal = {Biochemical Pharmacology},
year = {2022},
doi = {10.1016/j.bcp.2022.115045},
}
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