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Metformin: decelerates biomarkers of aging clocks

Signal Transduction and Targeted Therapy · 2024 · ▲ 21 citations

Telomere attrition Metformin Non-human primate Human

Abstract

A recent study published in Cell shows the widely known and used antidiabetic drug metformin, has geroprotective benefits in non-human male primates. 1 Metformin is a derivative of biguanide, synthesized in the 1920s and quickly became the first line off-label treatment for type 2 diabetes due to its efficacy in lowering plasma glucose levels.

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Provenance

Source: OpenAlex
DOI: 10.1038/s41392-024-02046-1
Canonical: link ↗
Fetched: 2026-08-24 MST

Cite this

APA

Zaki, R.A., & El‐Osta, A. (2024). Metformin: decelerates biomarkers of aging clocks. <em>Signal Transduction and Targeted Therapy</em>. https://doi.org/10.1038/s41392-024-02046-1

Vancouver

Zaki RA, El‐Osta A. Metformin: decelerates biomarkers of aging clocks. Signal Transduction and Targeted Therapy. 2024. doi:10.1038/s41392-024-02046-1.

BibTeX

@article{ram2024Metfor, title = {Metformin: decelerates biomarkers of aging clocks}, author = {Ram Abou Zaki and Assam El‐Osta}, journal = {Signal Transduction and Targeted Therapy}, year = {2024}, doi = {10.1038/s41392-024-02046-1}, }