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Gone with the Wnt/Notch: stem cells in laminopathies, progeria, and aging

The Journal of Cell Biology · 2008 · ▲ 76 citations

Stem-cell exhaustion Altered intercellular communication Human Mouse

Abstract

Specific mutations in the human gene encoding lamin A or in the lamin A-processing enzyme, Zmpste24, cause premature aging. New data on mice and humans suggest that these mutations affect adult stem cells by interfering with the Notch and Wnt signaling pathways.

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Provenance

Source: OpenAlex
DOI: 10.1083/jcb.200802155
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Fetched: 2026-08-21 MST

Cite this

APA

Meshorer, E., & Gruenbaum, Y. (2008). Gone with the Wnt/Notch: stem cells in laminopathies, progeria, and aging. <em>The Journal of Cell Biology</em>. https://doi.org/10.1083/jcb.200802155

Vancouver

Meshorer E, Gruenbaum Y. Gone with the Wnt/Notch: stem cells in laminopathies, progeria, and aging. The Journal of Cell Biology. 2008. doi:10.1083/jcb.200802155.

BibTeX

@article{eran2008Gonewi, title = {Gone with the Wnt/Notch: stem cells in laminopathies, progeria, and aging}, author = {Eran Meshorer and Yosef Gruenbaum}, journal = {The Journal of Cell Biology}, year = {2008}, doi = {10.1083/jcb.200802155}, }