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Deceptively simple but simply deceptive – <i>Caenorhabditis elegans</i> lifespan studies: Considerations for aging and antioxidant effects

Jan Gruber, Li Fang Ng, Suresh Poovathingal, Barry Halliwell

FEBS Letters · 2009 · ▲ 114 citations

Deregulated nutrient-sensing C. elegans Review
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Abstract

The nematode worm Caenorhabditis elegans (C. elegans) is increasingly popular as a model organism for aging studies as well as for testing antioxidants and other compounds for effects on longevity. However, results in the literature are sometimes confusing and contradictory. This review introduces C. elegans as a model organism, discusses aspects that make it attractive for aging and antioxidant research, and addresses some problems and potential artifacts.

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OpenAlex
DOI
10.1016/j.febslet.2009.09.051
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2026-06-30 MST

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APA
Gruber, J., Ng, L.F., Poovathingal, S., &amp; Halliwell, B. (2009). Deceptively simple but simply deceptive – <i>Caenorhabditis elegans</i> lifespan studies: Considerations for aging and antioxidant effects. <em>FEBS Letters</em>. https://doi.org/10.1016/j.febslet.2009.09.051
Vancouver
Gruber J, Ng LF, Poovathingal S, Halliwell B. Deceptively simple but simply deceptive – <i>Caenorhabditis elegans</i> lifespan studies: Considerations for aging and antioxidant effects. FEBS Letters. 2009. doi:10.1016/j.febslet.2009.09.051.
BibTeX
@article{jan2009Decept, title = {Deceptively simple but simply deceptive – <i>Caenorhabditis elegans</i> lifespan studies: Considerations for aging and antioxidant effects}, author = {Jan Gruber and Li Fang Ng and Suresh Poovathingal and Barry Halliwell}, journal = {FEBS Letters}, year = {2009}, doi = {10.1016/j.febslet.2009.09.051}, }

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