Open access · US-GOV
via ClinicalTrials.gov Clinical trial
A Randomized, Double-blind, Placebo-controlled Research Study Evaluating the Efficacy and Safety of Multi-dose Fecal Microbiota Transplantation (FMT) in Capsule Form as an Intervention to Slow Down the Rate of Biological Aging.
Authors not listed
Human Biome S.A. · 2026
Epigenetic alterations
Dysbiosis
Chronic inflammation
Microbiome / FMT
Human
Randomized controlled trial
Abstract
The goal of this clinical trial is to evaluate if multi-dose fecal microbiota transplantation (FMT) capsules can safely and effectively slow down biological aging and reduce chronic low-grade inflammation in adults aged 45 to 80 with metabolic neglect.
The main questions it aims to answer are:
* Can oral FMT capsules significantly slow the biological pace of aging as measured by the DunedinPACE epigenetic clock(definition)?
* Can FMT successfully reduce chronic systemic inflammation (measured by markers such as suPAR, IL-6, and hs-CRP)?
Researchers will compare participants receiving the active product to those receiving a matching placebo to see if the microbiome intervention improves metabolic health and cognitive function via the gut-brain axis.
Participants will:
* Undergo a short-term preparation phase involving targeted antibiotics and standard bowel cleansing.
* Receive an 2 initial induction doses of active product (or placebo) followed by 5 regular booster cycles administered approximately every 4 weeks.
* Attend periodic clinical visits for physical examinations, blood draws, stool sample collection (at home), and cognitive testing using the CANTAB platform and MoCA scale.
* Maintain a participant diary to record adverse events (AE), product administration, stool sample collection, and dietary habits.
◌ CITATION ONLY
Full text is not openly licensed for redistribution here. Read it at the source:
Provenance
- Source
- ClinicalTrials.gov
- Canonical
- link ↗
- Fetched
- 2026-11-04 MST
Cite this
APA
Anonymous. (2026). A Randomized, Double-blind, Placebo-controlled Research Study Evaluating the Efficacy and Safety of Multi-dose Fecal Microbiota Transplantation (FMT) in Capsule Form as an Intervention to Slow Down the Rate of Biological Aging. <em>Human Biome S.A.</em>. https://clinicaltrials.gov/study/NCT07912164
Vancouver
Anonymous. A Randomized, Double-blind, Placebo-controlled Research Study Evaluating the Efficacy and Safety of Multi-dose Fecal Microbiota Transplantation (FMT) in Capsule Form as an Intervention to Slow Down the Rate of Biological Aging. Human Biome S.A.. 2026.
BibTeX
@misc{anon2026ARando,
title = {A Randomized, Double-blind, Placebo-controlled Research Study Evaluating the Efficacy and Safety of Multi-dose Fecal Microbiota Transplantation (FMT) in Capsule Form as an Intervention to Slow Down the Rate of Biological Aging.},
author = {Anonymous},
journal = {Human Biome S.A.},
year = {2026},
}
Research neighborhood
References, citing works, and semantically nearest findings. Click a node to open it.
Related findings
Environmental Health Perspectives 2023
Open access · CC0
Arsenic Exposure and Epigenetic Aging: The Association with Cardiovascular Disease and All-Cause Mortality in the Strong Heart Study
npj Aging 2026
Open access · CC-BY
Sex-specific cognitive and metabolic effects of lifelong caloric restriction and sodium butyrate administration in aging rats
Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring 2024
Open access · CC-BY
Association of a pace of aging epigenetic clock with rate of cognitive decline in the Framingham Heart Study Offspring Cohort
Aging cell 2026
Open access · OA
LivAge: An Online Aging Clock for Murine Transcriptomic Age Estimation.
Circulation 2025
Citation only
Abstract MP71: Smoking and Biological Aging Acceleration Measured by Midlife Proteomic Aging Clocks: Insights from the Multi-Ethnic Study of Atherosclerosis (MESA)
Amazentis SA 2025
Open access · US-GOV