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A randomized controlled trial to isolate the effects of fasting and energy restriction on weight loss and metabolic health in lean adults

Iain Templeman, Harry Smith, Enhad A. Chowdhury, Yung-Chih Chen, Harriet A. Carroll, Drusus Johnson-Bonson, Aaron Hengist, Rowan Smith, Jade Creighton, David J. Clayton, Ian Varley, Leonidas G. Karagounis, Andrew Wilhelmsen, Kostas Tsintzas, Sue Reeves

Science Translational Medicine · 2021 · ▲ 113 citations

Abstract

> 0.05). Alternate-day fasting less effectively reduces body fat mass than a matched degree of daily energy restriction and without evidence of fasting-specific effects on metabolic regulation or cardiovascular health.

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Provenance

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OpenAlex
DOI
10.1126/scitranslmed.abd8034
Canonical
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2026-06-16 MST

Cite this

APA
Templeman, I., Smith, H., Chowdhury, E.A., Chen, Y., Carroll, H.A., Johnson-Bonson, D., Hengist, A., Smith, R., Creighton, J., Clayton, D.J., Varley, I., Karagounis, L.G., Wilhelmsen, A., Tsintzas, K., Reeves, S., Walhin, J., Gonzalez, J.T., Thompson, D., &amp; Betts, J.A. (2021). A randomized controlled trial to isolate the effects of fasting and energy restriction on weight loss and metabolic health in lean adults. <em>Science Translational Medicine</em>. https://doi.org/10.1126/scitranslmed.abd8034
Vancouver
Templeman I, Smith H, Chowdhury EA, Chen Y, Carroll HA, Johnson-Bonson D, et al. A randomized controlled trial to isolate the effects of fasting and energy restriction on weight loss and metabolic health in lean adults. Science Translational Medicine. 2021. doi:10.1126/scitranslmed.abd8034.
BibTeX
@unpublished{iain2021Arando, title = {A randomized controlled trial to isolate the effects of fasting and energy restriction on weight loss and metabolic health in lean adults}, author = {Iain Templeman and Harry Smith and Enhad A. Chowdhury and Yung-Chih Chen and Harriet A. Carroll and Drusus Johnson-Bonson and Aaron Hengist and Rowan Smith and Jade Creighton and David J. Clayton and Ian Varley and Leonidas G. Karagounis and Andrew Wilhelmsen and Kostas Tsintzas and Sue Reeves and Jean‐Philippe Walhin and Javier T. Gonzalez and Dylan Thompson and James A. Betts}, journal = {Science Translational Medicine}, year = {2021}, doi = {10.1126/scitranslmed.abd8034}, }

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