Author
Richard A. Miller
- Indexed works
- 73
- Total citations
- 14,664
- Active years
- 22
Collaborators
Works in the record
Nature 2009
Preprint · OA
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
Science 1996
Preprint · CC-BY
The Aging Immune System: Primer and Prospectus
The Journals of Gerontology Series A 2010
Open access · OA
Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice
Proceedings of the National Academy of Sciences 2001
Preprint · OA
Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production
Aging Cell 2005
Open access · OA
Methionine‐deficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF‐I and insulin levels, and increases hepatocyte MIF levels and stress resistance
Aging Cell 2012
Open access · OA
Rapamycin slows aging in mice
Aging Cell 2013
Open access · CC-BY
Rapamycin‐mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction
Aging Cell 2013
Open access · CC-BY
Acarbose, 17‐α‐estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males
Cell Metabolism 2017
Open access · OA
Using DNA Methylation Profiling to Evaluate Biological Age and Longevity Interventions
Nature 2001
Open access · OA
Extending the lifespan of long-lived mice
Aging Cell 2016
Open access · CC-BY
Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α‐glucosidase inhibitor or a Nrf2‐inducer
BMC Microbiology 2019
Open access · CC-BY
Changes in the gut microbiome and fermentation products concurrent with enhanced longevity in acarbose-treated mice
Aging Cell 2008
Open access · OA
Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice
Cell 2015
Open access · OA
Reduced Expression of MYC Increases Longevity and Enhances Healthspan
Aging Cell 2007
Open access · OA
An aging Interventions Testing Program: study design and interim report
Genome biology 2017
Open access · CC-BY
Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions
Milbank Quarterly 2002
Open access · OA
Extending Life: Scientific Prospects and Political Obstacles
Cell 2023
Preprint · OA
Distinct longevity mechanisms across and within species and their association with aging
AGE 2008
Open access · OA
Design of aging intervention studies: the NIA interventions testing program
EBioMedicine 2016
Open access · CC-BY
NIA Interventions Testing Program: Investigating Putative Aging Intervention Agents in a Genetically Heterogeneous Mouse Model
Aging Cell 2019
Open access · CC-BY
Acarbose improves health and lifespan in aging HET3 mice
JCI Insight 2020
Open access · CC-BY
Canagliflozin extends life span in genetically heterogeneous male but not female mice
Aging Cell 2021
Open access · CC-BY
17‐a‐estradiol late in life extends lifespan in aging UM‐HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex
Aging Cell 2017
Open access · CC-BY
Sex differences in lifespan extension with acarbose and 17‐α estradiol: gonadal hormones underlie male‐specific improvements in glucose tolerance and mTORC 2 signaling
Aging Cell 2019
Open access · CC-BY
Glycine supplementation extends lifespan of male and female mice
The Journals of Gerontology Series A 2013
Open access · OA
Assessment of Mitochondrial Biogenesis and mTORC1 Signaling During Chronic Rapamycin Feeding in Male and Female Mice
Aging Cell 2015
Open access · CC-BY
Growth hormone modulates hypothalamic inflammation in long‐lived pituitary dwarf mice
Aging Cell 2017
Open access · CC-BY
Anti‐aging drugs reduce hypothalamic inflammation in a sex‐specific manner
Science 2022
Preprint · OA
Sex- and age-dependent genetics of longevity in a heterogeneous mouse population
Aging Cell 2014
Open access · CC-BY
ATF 4 activity: a common feature shared by many kinds of slow‐aging mice
Aging Cell 2022
Open access · CC-BY
Lifespan benefits for the combination of rapamycin plus acarbose and for captopril in genetically heterogeneous mice
Aging Cell 2018
Open access · CC-BY
Male lifespan extension with 17‐α estradiol is linked to a sex‐specific metabolomic response modulated by gonadal hormones in mice
Aging Cell 2019
Open access · CC-BY
17‐α estradiol ameliorates age‐associated sarcopenia and improves late‐life physical function in male mice but not in females or castrated males
Aging Cell 2021
Open access · CC-BY
Cap‐independent translation: A shared mechanism for lifespan extension by rapamycin, acarbose, and 17α‐estradiol
Oncotarget 2016
Open access · CC-BY
Overactive mTOR signaling leads to endometrial hyperplasia in aged women and mice
GeroScience 2019
Open access · OA
Cellular energetics and mitochondrial uncoupling in canine aging
Aging Cell 2019
Open access · CC-BY
Improved mitochondrial stress response in long‐lived Snell dwarf mice
Connective Tissue Research 2019
Preprint · OA
Naturally occurring osteoarthritis in male mice with an extended lifespan
GeroScience 2022
Open access · CC-BY
Canagliflozin retards age-related lesions in heart, kidney, liver, and adrenal gland in genetically heterogenous male mice
Nature Communications 2023
Open access · CC-BY
Evolution of high-molecular-mass hyaluronic acid is associated with subterranean lifestyle
JCI Insight 2020
Open access · CC-BY
Acarbose has sex-dependent and -independent effects on age-related physical function, cardiac health, and lipid biology
Aging Cell 2017
Open access · CC-BY
Mitochondrial thioredoxin reductase 2 is elevated in long‐lived primate as well as rodent species and extends fly mean lifespan
Immunity & Ageing 2022
Open access · CC-BY
Rapamycin, Acarbose and 17α-estradiol share common mechanisms regulating the MAPK pathways involved in intracellular signaling and inflammation
Nature Aging 2024
Preprint · OA
Late-life protein or isoleucine restriction impacts physiological and molecular signatures of aging
GeroScience 2024
Preprint · OA
Lifespan effects in male UM-HET3 mice treated with sodium thiosulfate, 16-hydroxyestriol, and late-start canagliflozin
The Journals of Gerontology Series A 2019
Open access · OA
Life-span Extension Drug Interventions Affect Adipose Tissue Inflammation in Aging
GeroScience 2023
Preprint · OA
Four anti-aging drugs and calorie-restricted diet produce parallel effects in fat, brain, muscle, macrophages, and plasma of young mice
Aging Cell 2022
Open access · CC-BY
Cap‐independent translation of GPLD1 enhances markers of brain health in long‐lived mutant and drug‐treated mice
Ageing Research Reviews 2023
Preprint · OA
Revisiting adipose thermogenesis for delaying aging and age-related diseases: Opportunities and challenges
Life Sciences 2023
Preprint · CC-BY