Author
Paul D. Robbins
- Indexed works
- 65
- Total citations
- 15,869
- Active years
- 15
Collaborators
Works in the record
Cell 2019
Open access · OA
Cellular Senescence: Defining a Path Forward
Nature Communications 2017
Open access · CC-BY
Cellular senescence mediates fibrotic pulmonary disease
Aging Cell 2015
Open access · CC-BY
Identification of a novel senolytic agent, navitoclax, targeting the Bcl‐2 family of anti‐apoptotic factors
Nature Communications 2022
Open access · CC-BY
A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues
EBioMedicine 2018
Open access · CC-BY
Fisetin is a senotherapeutic that extends health and lifespan
Aging 2017
Open access · CC-BY
New agents that target senescent cells: the flavone, fisetin, and the BCL-XL inhibitors, A1331852 and A1155463
Nature Communications 2017
Open access · CC-BY
Identification of HSP90 inhibitors as a novel class of senolytics
Journal of Clinical Investigation 2022
Open access · CC-BY
Cellular senescence: a key therapeutic target in aging and diseases
FEBS Journal 2022
Citation only
Targeting cellular senescence with senotherapeutics: senolytics and senomorphics
PLoS ONE 2010
Open access · CC-BY
SIRT1 Negatively Regulates the Mammalian Target of Rapamycin
Cell 2024
Open access · CC-BY
Guidelines for minimal information on cellular senescence experimentation in vivo
Aging Cell 2020
Open access · CC-BY
Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice
The Annual Review of Pharmacology and Toxicology 2020
Open access · OA
Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span
Frontiers in Aging 2022
Open access · CC-BY
Immune Senescence, Immunosenescence and Aging
Annual Review of Biochemistry 2018
Open access · OA
Nuclear Genomic Instability and Aging
The Journals of Gerontology Series A 2021
Preprint · OA
Senolytic Combination of Dasatinib and Quercetin Alleviates Intestinal Senescence and Inflammation and Modulates the Gut Microbiome in Aged Mice
Biomolecules 2023
Open access · CC-BY
Cellular Senescence in Intervertebral Disc Aging and Degeneration: Molecular Mechanisms and Potential Therapeutic Opportunities
Nature Reviews Drug Discovery 2018
Citation only
Senotherapeutics for healthy ageing
Journal of Orthopaedic Research® 2013
Preprint · OA
Mitochondrial‐derived reactive oxygen species (ROS) play a causal role in aging‐related intervertebral disc degeneration
Aging Cell 2019
Open access · CC-BY
Systemic clearance of p16 INK4a ‐positive senescent cells mitigates age‐associated intervertebral disc degeneration
Nature reviews. Immunology 2022
Open access · OA
COVID-19 and cellular senescence
EBioMedicine 2019
Open access · CC-BY
Fibrates as drugs with senolytic and autophagic activity for osteoarthritis therapy
Immunity & Ageing 2023
Open access · CC-BY
Aging and chronic inflammation: highlights from a multidisciplinary workshop
Endocrinology 2021
Open access · OA
Role of Cellular Senescence in Type II Diabetes
Journal of Bone and Mineral Research 2012
Open access · OA
DNA damage drives accelerated bone aging via an NF-<b>κ</b>B–dependent mechanism
Aging 2020
Preprint · CC-BY
ATM is a key driver of NF-κB-dependent DNA-damage-induced senescence, stem cell dysfunction and aging
Aging Cell 2017
Open access · CC-BY
Circulating levels of monocyte chemoattractant protein‐1 as a potential measure of biological age in mice and frailty in humans
Cell Cycle 2018
Open access · OA
Hsp90 inhibitors as senolytic drugs to extend healthy aging
Stem Cell Investigation 2017
Open access · CC-BY
Extracellular vesicles and aging
Aging 2021
Open access · CC-BY
SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3
Aging Cell 2021
Open access · CC-BY
Novel small molecule inhibition of IKK/NF‐κB activation reduces markers of senescence and improves healthspan in mouse models of aging
GeroScience 2020
Open access · OA
Heterochronic parabiosis regulates the extent of cellular senescence in multiple tissues
bioRxiv (Cold Spring Harbor Laboratory) 2021
Preprint · OA
A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways Across Tissues
GeroScience 2023
Open access · CC-BY
Astaxanthin and meclizine extend lifespan in UM-HET3 male mice; fisetin, SG1002 (hydrogen sulfide donor), dimethyl fumarate, mycophenolic acid, and 4-phenylbutyrate do not significantly affect lifespan in either sex at the doses and schedules used
Journal of the American Geriatrics Society 2021
Open access · CC-BY
Fisetin for COVID ‐19 in skilled nursing facilities: Senolytic trials in the COVID era
Molecular Therapy — Methods & Clinical Development 2019
Open access · CC-BY
Rapamycin Rescues Age-Related Changes in Muscle-Derived Stem/Progenitor Cells from Progeroid Mice
Journal of Cachexia Sarcopenia and Muscle 2022
Open access · CC-BY
Reduction of senescent fibro‐adipogenic progenitors in progeria‐aged muscle by senolytics rescues the function of muscle stem cells
Mechanisms of Ageing and Development 2019
Citation only
Oxidative stress-induced senescence markedly increases disc cell bioenergetics
Redox Biology 2018
Open access · CC-BY
Dysregulation of DAF-16/FOXO3A-mediated stress responses accelerates oxidative DNA damage induced aging
Current Opinion in Pharmacology 2021
Preprint · OA
Intersection of immunometabolism and immunosenescence during aging
Current Diabetes Reports 2022
Preprint · OA
Cellular Senescence in Obesity and Associated Complications: a New Therapeutic Target
Journal of Orthopaedic Research® 2016
Open access · CC-BY
mTOR signaling plays a critical role in the defects observed in muscle-derived stem/progenitor cells isolated from a murine model of accelerated aging
Ageing Research Reviews 2024
Open access · OA
Developing transcriptomic signatures as a biomarker of cellular senescence
Cell Metabolism 2024
Open access · OA
A nutrigeroscience approach: Dietary macronutrients and cellular senescence
Journal of Visualized Experiments 2019
Citation only
SA-β-Galactosidase-Based Screening Assay for the Identification of Senotherapeutic Drugs
bioRxiv (Cold Spring Harbor Laboratory) 2023
Preprint · CC-BY
Distinct secretomes in p16- and p21- positive senescent cells across tissues
Aging Cell 2024
Open access · CC-BY
Clinical validation of C 12 FDG as a marker associated with senescence and osteoarthritic phenotypes
Current Protocols in Cytometry 2017
Citation only
Quantitative Analysis of Cellular Senescence in Culture and In Vivo
Cell Metabolism 2025
Preprint · OA
Endothelial senescent-cell-specific clearance alleviates metabolic dysfunction in obese mice
Journal of Extracellular Vesicles 2025
Open access · CC-BY