Author
Nino Giorgadze
- Indexed works
- 17
- Total citations
- 10,535
- Active years
- 8
Collaborators
Works in the record
Aging Cell 2015
Open access · CC-BY
The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs
Nature Medicine 2018
Preprint · OA
Senolytics improve physical function and increase lifespan in old age
EBioMedicine 2019
Open access · CC-BY
Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease
Aging Cell 2015
Open access · CC-BY
Identification of a novel senolytic agent, navitoclax, targeting the Bcl‐2 family of anti‐apoptotic factors
Proceedings of the National Academy of Sciences 2015
Open access · OA
JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age
Aging 2017
Open access · CC-BY
New agents that target senescent cells: the flavone, fisetin, and the BCL-XL inhibitors, A1331852 and A1155463
eLife 2015
Open access · CC-BY
Targeting senescent cells enhances adipogenesis and metabolic function in old age
Cell Metabolism 2019
Open access · CC-BY
Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis
EBioMedicine 2022
Open access · CC-BY
Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans
Aging 2021
Open access · CC-BY
SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3
EBioMedicine 2020
Open access · CC-BY
Corrigendum to ‘Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease’ EBioMedicine 47 (2019) 446–456
Cell Metabolism 2025
Preprint · OA
Endothelial senescent-cell-specific clearance alleviates metabolic dysfunction in obese mice
Aging Cell 2025
Open access · CC-BY
Senolytic‐Resistant Senescent Cells Have a Distinct SASP Profile and Functional Impact: The Path to Developing Senosensitizers
npj Aging 2025
Open access · CC-BY
Space radiation induces distinct senescent phenotypes: Implications for space travel
Innovation in Aging 2020
Open access · CC-BY
Effect of Combined Dasatinib and Fisetin Treatment on Senescent Cell Clearance in Monkeys
Innovation in Aging 2022
Open access · CC-BY
ORALLY ACTIVE, CLINICALLY TRANSLATABLE SENOLYTICS RESTORE Α-KLOTHO IN MICE AND HUMANS
bioRxiv (Cold Spring Harbor Laboratory) 2025
Preprint · OA