Nino Giorgadze

Aging Cell · 2015

⊕ Open access · CC-BY

The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs

▲ 2,514

Nature Medicine · 2018

⊕ Preprint · OA

Senolytics improve physical function and increase lifespan in old age

▲ 2,318

EBioMedicine · 2019

⊕ Open access · CC-BY

Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease

▲ 1,359

Aging Cell · 2015

⊕ Open access · CC-BY

Identification of a novel senolytic agent, navitoclax, targeting the Bcl‐2 family of anti‐apoptotic factors

▲ 1,143

Proceedings of the National Academy of Sciences · 2015

⊕ Open access · OA

JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age

▲ 924

Aging · 2017

⊕ Open access · CC-BY

New agents that target senescent cells: the flavone, fisetin, and the BCL-XL inhibitors, A1331852 and A1155463

▲ 745

eLife · 2015

⊕ Open access · CC-BY

Targeting senescent cells enhances adipogenesis and metabolic function in old age

▲ 604

Cell Metabolism · 2019

⊕ Open access · CC-BY

Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis

▲ 552

EBioMedicine · 2022

⊕ Open access · CC-BY

Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans

▲ 95

Aging · 2021

⊕ Open access · CC-BY

SARS-CoV-2 causes senescence in human cells and exacerbates the senescence-associated secretory phenotype through TLR-3

▲ 90

EBioMedicine · 2020

⊕ Open access · CC-BY

Corrigendum to ‘Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease’ EBioMedicine 47 (2019) 446–456

▲ 59

Cell Metabolism · 2025

⊕ Preprint · OA

Endothelial senescent-cell-specific clearance alleviates metabolic dysfunction in obese mice

▲ 18

Aging Cell · 2025

⊕ Open access · CC-BY

Senolytic‐Resistant Senescent Cells Have a Distinct SASP Profile and Functional Impact: The Path to Developing Senosensitizers

▲ 7

Innovation in Aging · 2020

⊕ Open access · CC-BY

Effect of Combined Dasatinib and Fisetin Treatment on Senescent Cell Clearance in Monkeys

▲ 2