Nathan K. LeBrasseur

Nature · 2011

⊕ Preprint · OA

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

▲ 3,617

Aging Cell · 2015

⊕ Open access · CC-BY

The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs

▲ 2,410

Nature Medicine · 2018

◌ Citation only

Senolytics improve physical function and increase lifespan in old age

▲ 2,218

Nature Communications · 2017

⊕ Open access · CC-BY

Cellular senescence mediates fibrotic pulmonary disease

▲ 1,560

EBioMedicine · 2019

⊕ Open access · CC-BY

Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study

▲ 1,177

Nature Medicine · 2017

⊕ Preprint · OA

Targeting cellular senescence prevents age-related bone loss in mice

▲ 1,131

Nature Communications · 2022

⊕ Open access · CC-BY

A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues

▲ 959

Proceedings of the National Academy of Sciences · 2015

⊕ Open access · OA

JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age

▲ 885

Journal of Bone and Mineral Research · 2016

⊕ Preprint · OA

Identification of Senescent Cells in the Bone Microenvironment

▲ 539

Diabetes · 2015

⊕ Open access · OA

Cellular Senescence in Type 2 Diabetes: A Therapeutic Opportunity

▲ 412

Aging Cell · 2021

⊕ Open access · CC-BY

Whole‐body senescent cell clearance alleviates age‐related brain inflammation and cognitive impairment in mice

▲ 400

JCI Insight · 2020

⊕ Open access · CC-BY

The senescence-associated secretome as an indicator of age and medical risk

▲ 378

Diabetes · 2016

⊕ Open access · OA

Exercise Prevents Diet-Induced Cellular Senescence in Adipose Tissue

▲ 258

Nestlé Nutrition Institute Workshop series · 2015

⊕ Preprint · OA

Cellular Senescence and the Biology of Aging, Disease, and Frailty

▲ 150

Mechanisms of Ageing and Development · 2021

⊕ Preprint · OA

Skeletal muscle aging, cellular senescence, and senotherapeutics: Current knowledge and future directions

▲ 85

Molecular Metabolism · 2022

⊕ Open access · CC-BY

p21 induces a senescence program and skeletal muscle dysfunction

▲ 83

Aging Cell · 2023

⊕ Open access · CC-BY

Biomarkers of cellular senescence and risk of death in humans

▲ 79

Aging Cell · 2021

⊕ Open access · CC-BY

Novel small molecule inhibition of IKK/NF‐κB activation reduces markers of senescence and improves healthspan in mouse models of aging

▲ 77

GeroScience · 2022

⊕ Open access · OA

Associations between biomarkers of cellular senescence and physical function in humans: observations from the lifestyle interventions for elders (LIFE) study

▲ 71

bioRxiv (Cold Spring Harbor Laboratory) · 2021

⊕ Preprint · OA

A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways Across Tissues

▲ 59

bioRxiv (Cold Spring Harbor Laboratory) · 2023

⊕ Preprint · CC-BY

Distinct secretomes in p16- and p21- positive senescent cells across tissues

▲ 27

The Journals of Gerontology Series A · 2023

⊕ Preprint · OA

Caloric Restriction Intervention Alters Specific Circulating Biomarkers of the Senescence-Associated Secretome in Middle-Aged and Older Adults With Obesity and Prediabetes in an 18-Week Randomized Controlled Trial

▲ 24