Author
João F. Passos
- Indexed works
- 46
- Total citations
- 19,317
- Active years
- 15
Collaborators
Works in the record
Cell 2019
Open access · OA
Cellular Senescence: Defining a Path Forward
Nature Communications 2017
Open access · CC-BY
Cellular senescence mediates fibrotic pulmonary disease
EBioMedicine 2019
Open access · CC-BY
Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease
Nature Communications 2017
Open access · CC-BY
Cellular senescence drives age-dependent hepatic steatosis
Nature Communications 2022
Open access · CC-BY
A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues
Molecular Systems Biology 2010
Open access · OA
Feedback between p21 and reactive oxygen production is necessary for cell senescence
Nature Communications 2012
Open access · CC-BY
Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence
Nature Communications 2014
Open access · CC-BY
Chronic inflammation induces telomere dysfunction and accelerates ageing in mice
PLoS Biology 2007
Open access · CC-BY
Mitochondrial Dysfunction Accounts for the Stochastic Heterogeneity in Telomere-Dependent Senescence
Nature Cell Biology 2022
Open access · OA
Telomere dysfunction in ageing and age-related diseases
Cell Metabolism 2019
Open access · CC-BY
Obesity-Induced Cellular Senescence Drives Anxiety and Impairs Neurogenesis
The EMBO Journal 2018
Open access · OA
Mitochondrial inner membrane permeabilisation enables mtDNA release during apoptosis
Nature Communications 2019
Open access · CC-BY
Senescent cells evade immune clearance via HLA-E-mediated NK and CD8+ T cell inhibition
EBioMedicine 2017
Open access · CC-BY
Telomeres and Cell Senescence - Size Matters Not
Aging Cell 2021
Open access · CC-BY
Whole‐body senescent cell clearance alleviates age‐related brain inflammation and cognitive impairment in mice
Genes & Development 2020
Preprint · CC-BY
Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence
Cell 2024
Open access · CC-BY
Guidelines for minimal information on cellular senescence experimentation in vivo
The Annual Review of Pharmacology and Toxicology 2020
Open access · OA
Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span
Mechanisms of Ageing and Development 2017
Open access · CC-BY
Stress, cell senescence and organismal ageing
FEBS Letters 2019
Open access · OA
Mitochondrial dysfunction and cell senescence: deciphering a complex relationship
FEBS Journal 2022
Preprint · OA
Cellular senescence: all roads lead to mitochondria
Nature Communications 2020
Open access · CC-BY
Senolytics prevent mt-DNA-induced inflammation and promote the survival of aged organs following transplantation
Longevity & Healthspan 2014
Open access · CC-BY
Telomeres, oxidative stress and inflammatory factors: partners in cellular senescence?
Trends in Molecular Medicine 2020
Preprint · OA
Reducing Senescent Cell Burden in Aging and Disease
Aging Cell 2020
Open access · CC-BY
On the evolution of cellular senescence
Pharmacology & Therapeutics 2017
Open access · CC-BY
Mitochondria, telomeres and cell senescence: Implications for lung ageing and disease
Aging Cell 2020
Open access · CC-BY
Clearance of senescent cells during cardiac ischemia–reperfusion injury improves recovery
Biochimica et Biophysica Acta (BBA) - Bioenergetics 2015
Open access · OA
Mitochondria: Are they causal players in cellular senescence?
Journal of Bone and Mineral Research 2020
Open access · OA
Targeted Reduction of Senescent Cell Burden Alleviates Focal Radiotherapy-Related Bone Loss
Nature Communications 2020
Open access · CC-BY
Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk
Free Radical Biology and Medicine 2018
Preprint · OA
Mitochondria and cellular senescence: Implications for musculoskeletal ageing
Aging Cell 2018
Open access · CC-BY
Rapamycin improves healthspan but not inflammaging in nfκb1−/− mice
Aging Cell 2020
Open access · CC-BY
Anti‐inflammatory treatment rescues memory deficits during aging in nfkb1−/− mice
Cardiovascular Drugs and Therapy 2020
Open access · CC-BY
Therapeutic Potential of Senolytics in Cardiovascular Disease
EBioMedicine 2020
Open access · CC-BY
Corrigendum to ‘Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease’ EBioMedicine 47 (2019) 446–456
bioRxiv (Cold Spring Harbor Laboratory) 2021
Preprint · OA
A New Gene Set Identifies Senescent Cells and Predicts Senescence-Associated Pathways Across Tissues
Biogerontology 2023
Preprint · OA
Telomeres, cellular senescence, and aging: past and future
Journal of Bone and Mineral Research 2020
Open access · OA
Bone Marrow Adiposity in Models of Radiation- and Aging-Related Bone Loss Is Dependent on Cellular Senescence
The Journal of Immunology 2021
Open access · CC-BY
Moderate Exercise Inhibits Age-Related Inflammation, Liver Steatosis, Senescence, and Tumorigenesis
American Journal of Physiology-Lung Cellular and Molecular Physiology 2022
Preprint · OA
Cellular senescence is increased in airway smooth muscle cells of elderly persons with asthma
bioRxiv (Cold Spring Harbor Laboratory) 2023
Preprint · CC-BY
Distinct secretomes in p16- and p21- positive senescent cells across tissues
Age and Ageing 2023
Open access · CC-BY
New Horizons in cellular senescence for clinicians
EMBO Molecular Medicine 2026
Open access · CC-BY
Tomatidine is a senotherapeutic compound that improves cognitive function and reduces cellular senescence in aged mice
Research Square 2022
Preprint · CC-BY
Sub-lethal apoptotic stress enables mtDNA release during senescence and drives the SASP
Innovation in Aging 2024
Open access · CC-BY
NEW INSIGHTS INTO MITOCHONDRIA AND CELLULAR SENESCENCE
bioRxiv (Cold Spring Harbor Laboratory) 2025
Preprint · OA