Author
James F. Nelson
- Indexed works
- 33
- Total citations
- 8,122
- Active years
- 17
Collaborators
Works in the record
Nature 2009
Preprint · OA
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
The Journals of Gerontology Series A 2010
Open access · OA
Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice
Aging Cell 2013
Open access · CC-BY
Rapamycin‐mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction
Aging Cell 2013
Open access · CC-BY
Acarbose, 17‐α‐estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males
Aging Cell 2016
Open access · CC-BY
Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α‐glucosidase inhibitor or a Nrf2‐inducer
Aging Cell 2008
Open access · OA
Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice
Aging Cell 2007
Open access · OA
An aging Interventions Testing Program: study design and interim report
AGE 2008
Open access · OA
Design of aging intervention studies: the NIA interventions testing program
Aging Cell 2019
Open access · CC-BY
Acarbose improves health and lifespan in aging HET3 mice
JCI Insight 2020
Open access · CC-BY
Canagliflozin extends life span in genetically heterogeneous male but not female mice
Aging Cell 2011
Open access · OA
Fat maintenance is a predictor of the murine lifespan response to dietary restriction
Aging Cell 2021
Open access · CC-BY
17‐a‐estradiol late in life extends lifespan in aging UM‐HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex
Aging Cell 2020
Open access · CC-BY
Rapamycin‐mediated mouse lifespan extension: Late‐life dosage regimes with sex‐specific effects
Aging Cell 2019
Open access · CC-BY
Glycine supplementation extends lifespan of male and female mice
The Journals of Gerontology Series A 2001
Citation only
Neuroendocrine and Pharmacological Manipulations to Assess How Caloric Restriction Increases Life Span
Science 2022
Preprint · OA
Sex- and age-dependent genetics of longevity in a heterogeneous mouse population
Aging Cell 2022
Open access · CC-BY
Lifespan benefits for the combination of rapamycin plus acarbose and for captopril in genetically heterogeneous mice
GeroScience 2023
Open access · CC-BY
Astaxanthin and meclizine extend lifespan in UM-HET3 male mice; fisetin, SG1002 (hydrogen sulfide donor), dimethyl fumarate, mycophenolic acid, and 4-phenylbutyrate do not significantly affect lifespan in either sex at the doses and schedules used
Aging Cell 2019
Open access · CC-BY
Genetically heterogeneous mice exhibit a female survival advantage that is age‐ and site‐specific: Results from a large multi‐site study
Experimental Gerontology 2013
Preprint · OA
Genetic variation in responses to dietary restriction — An unbiased tool for hypothesis testing
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2018
Open access · OA
Genetic cartography of longevity in humans and mice: Current landscape and horizons
GeroScience 2024
Preprint · OA
Lifespan effects in male UM-HET3 mice treated with sodium thiosulfate, 16-hydroxyestriol, and late-start canagliflozin
bioRxiv (Cold Spring Harbor Laboratory) 2020
Preprint · OA
Canagliflozin Extends Lifespan in Genetically Heterogeneous Male But Not Female Mice
GeroScience 2024
Open access · CC-BY
The Gehan test identifies life-extending compounds overlooked by the log-rank test in the NIA Interventions Testing Program: Metformin, Enalapril, caffeic acid phenethyl ester, green tea extract, and 17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride
Public Policy & Aging Report 2023
Preprint · OA
Sex Differences in Mouse Longevity and Responses to Geroprotective Drugs: Implications for Human Intervention
Nature Communications 2025
Open access · CC-BY
Deciphering the timing and impact of life-extending interventions: temporal efficacy profiler distinguishes early, midlife, and senescence phase efficacies
GeroScience 2025
Open access · CC-BY
Extension of lifespan by epicatechin, halofuginone and mitoglitazone in male but not female genetically heterogeneous mice
bioRxiv (Cold Spring Harbor Laboratory) 2024
Preprint · CC-BY
Deciphering the Timing and Impact of Life-extending Interventions: Temporal Efficacy Profiler Distinguishes Early, Midlife, and Senescence Phase Efficacies
The Journals of Gerontology Series A 2025
Open access · OA
Sex as a major determinant of pro-longevity drug efficacy: a review of two decades of the NIA Interventions Testing Program
GeroScience 2025
Open access · CC-BY
Life-extending interventions do not necessarily result in compression of morbidity: a case example offering a robust statistical approach
bioRxiv (Cold Spring Harbor Laboratory) 2025
Preprint · CC-BY
Genetic Modulation of Lifespan: Dynamic Effects, Sex Differences, and Body Weight Trade-offs
GeroScience 2025
Open access · CC-BY
End-of-life pathology in UM-HET3 mice treated with 16 α‑hydroxyestradiol or late‑start canagliflozin
bioRxiv (Cold Spring Harbor Laboratory) 2026
Preprint · CC-BY