Charles Brenner

Nature Communications 2016

Open access · CC-BY

Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

▲ 696

Cell Reports 2019

Open access · CC-BY

Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures

▲ 449

Nature Communications 2016

Open access · CC-BY

NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells

▲ 378

Circulation 2017

Open access · OA

Nicotinamide Riboside Preserves Cardiac Function in a Mouse Model of Dilated Cardiomyopathy

▲ 358

Cell Metabolism 2018

Open access · OA

Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice

▲ 331

Scientific Reports 2016

Open access · CC-BY

Nicotinamide Riboside Opposes Type 2 Diabetes and Neuropathy in Mice

▲ 300

Scientific Reports 2019

Open access · CC-BY

Safety and Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) in a Randomized, Double-Blind, Placebo-controlled Clinical Trial of Healthy Overweight Adults

▲ 210

Computational and Structural Biotechnology Journal 2013

Open access · CC-BY

TARGETED, LCMS-BASED METABOLOMICS FOR QUANTITATIVE MEASUREMENT OF NAD + METABOLITES

▲ 203

Molecular Cell 2020

Open access · OA

NAD+ Controls Circadian Reprogramming through PER2 Nuclear Translocation to Counter Aging

▲ 180

Science Advances 2023

Open access · CC-BY

Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study

▲ 125

Molecular Metabolism 2017

Open access · CC-BY

Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells

▲ 121

Journal of Nutrition 2016

Open access · OA

Nicotinamide Riboside Is a Major NAD+ Precursor Vitamin in Cow Milk

▲ 112

BMC Chemical Biology 2010

Open access · CC-BY

NAD+ metabolite levels as a function of vitamins and calorie restriction: evidence for different mechanisms of longevity

▲ 83

American Journal of Physiology-Heart and Circulatory Physiology 2017

Open access · OA

Emerging potential benefits of modulating NAD + metabolism in cardiovascular disease

▲ 65

GeroScience 2023

Preprint · OA

A randomized placebo-controlled trial of nicotinamide riboside in older adults with mild cognitive impairment

▲ 48

Mechanisms of Ageing and Development 2020

Open access · CC-BY

Targeting NAD+ in translational research to relieve diseases and conditions of metabolic stress and ageing

▲ 47

Life Metabolism 2022

Open access · CC-BY

Sirtuins are not conserved longevity genes

▲ 42

Nature Metabolism 2022

Open access · OA

Viral infection as an NAD+ battlefield

▲ 41

The EMBO Journal 2024

Open access · CC-BY

Control of NAD+ homeostasis by autophagic flux modulates mitochondrial and cardiac function

▲ 34

Hepatology Communications 2020

Open access · CC-BY

Nicotinamide Adenine Dinucleotide Metabolome Is Functionally Depressed in Patients Undergoing Liver Transplantation for Alcohol‐Related Liver Disease

▲ 27

PLoS Biology 2015

Open access · CC-BY

Calorie Restriction-Mediated Replicative Lifespan Extension in Yeast Is Non-Cell Autonomous

▲ 22

bioRxiv (Cold Spring Harbor Laboratory) 2019

Preprint · CC-BY

Nicotinamide riboside augments the human skeletal muscle NAD + metabolome and induces transcriptomic and anti-inflammatory signatures in aged subjects: a placebo-controlled, randomized trial

▲ 11

Heliyon 2024

Open access · CC-BY

Nicotinamide riboside first alleviates symptoms but later downregulates dopamine metabolism in proteasome inhibition mouse model of Parkinson's disease

▲ 7

bioRxiv (Cold Spring Harbor Laboratory) 2021

Preprint · CC-BY

Nicotinamide riboside alleviates Parkinson’s disease symptoms but downregulates dopamine metabolism upon lactacystin-induced proteostasis failure

▲ 3

bioRxiv (Cold Spring Harbor Laboratory) 2024

Preprint · CC-BY

Oral supplementation with Nicotinamide Riboside treatment protects RGCs in DBA/2J mouse model

▲ 2

Research Square 2020

Preprint · CC-BY

Inhibition of CD38 and supplementation of nicotinamide riboside ameliorate lipopolysaccharide-induced neuroinflammation in the hippocampus

▲ 2

2016

Preprint · OA

Novel NAD+ metabolomic technologies and their applications to Nicotinamide Riboside interventions

▲ 1

Collaborators

Works in the record

Nicotinamide riboside is uniquely and orally bioavailable in mice and humans

Nicotinamide Riboside Augments the Aged Human Skeletal Muscle NAD+ Metabolome and Induces Transcriptomic and Anti-inflammatory Signatures

NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells

Nicotinamide Riboside Preserves Cardiac Function in a Mouse Model of Dilated Cardiomyopathy

Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice

Nicotinamide Riboside Opposes Type 2 Diabetes and Neuropathy in Mice

Safety and Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) in a Randomized, Double-Blind, Placebo-controlled Clinical Trial of Healthy Overweight Adults

TARGETED, LCMS-BASED METABOLOMICS FOR QUANTITATIVE MEASUREMENT OF NAD + METABOLITES

NAD+ Controls Circadian Reprogramming through PER2 Nuclear Translocation to Counter Aging

Nicotinamide riboside improves muscle mitochondrial biogenesis, satellite cell differentiation, and gut microbiota in a twin study

Nicotinamide riboside kinases display redundancy in mediating nicotinamide mononucleotide and nicotinamide riboside metabolism in skeletal muscle cells

Nicotinamide Riboside Is a Major NAD+ Precursor Vitamin in Cow Milk

NAD+ metabolite levels as a function of vitamins and calorie restriction: evidence for different mechanisms of longevity

Emerging potential benefits of modulating NAD + metabolism in cardiovascular disease

A randomized placebo-controlled trial of nicotinamide riboside in older adults with mild cognitive impairment

Targeting NAD+ in translational research to relieve diseases and conditions of metabolic stress and ageing

Sirtuins are not conserved longevity genes

Viral infection as an NAD+ battlefield

Control of NAD+ homeostasis by autophagic flux modulates mitochondrial and cardiac function

Nicotinamide Adenine Dinucleotide Metabolome Is Functionally Depressed in Patients Undergoing Liver Transplantation for Alcohol‐Related Liver Disease

Calorie Restriction-Mediated Replicative Lifespan Extension in Yeast Is Non-Cell Autonomous

Nicotinamide riboside augments the human skeletal muscle NAD + metabolome and induces transcriptomic and anti-inflammatory signatures in aged subjects: a placebo-controlled, randomized trial

Nicotinamide riboside first alleviates symptoms but later downregulates dopamine metabolism in proteasome inhibition mouse model of Parkinson's disease

Nicotinamide riboside alleviates Parkinson’s disease symptoms but downregulates dopamine metabolism upon lactacystin-induced proteostasis failure

Oral supplementation with Nicotinamide Riboside treatment protects RGCs in DBA/2J mouse model

Inhibition of CD38 and supplementation of nicotinamide riboside ameliorate lipopolysaccharide-induced neuroinflammation in the hippocampus

Novel NAD+ metabolomic technologies and their applications to Nicotinamide Riboside interventions