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Umbilical Cord as Prospective Source for Mesenchymal Stem Cell‐Based Therapy

I. V. Arutyunyan, Andrey Elchaninov, А. В. Макаров, Timur Fatkhudinov

Stem Cells International · 2016 · ▲ 258 citations

Stem-cell exhaustion Altered intercellular communication Stem-cell therapy Human Preclinical / animal Review

Abstract

The paper presents current evidence on the properties of human umbilical cord-derived mesenchymal stem cells, including origin, proliferative potential, plasticity, stability of karyotype and phenotype, transcriptome, secretome, and immunomodulatory activity. A review of preclinical studies and clinical trials using this cell type is performed. Prospects for the use of mesenchymal stem cells, derived from the umbilical cord, in cell transplantation are associated with the need for specialized biobanking and transplant standardization criteria.

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Provenance

Source: OpenAlex
DOI: 10.1155/2016/6901286
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Fetched: 2026-06-21 MST

Cite this

APA

Arutyunyan, I.V., Elchaninov, A., Макаров, �.�., & Fatkhudinov, T. (2016). Umbilical Cord as Prospective Source for Mesenchymal Stem Cell‐Based Therapy. <em>Stem Cells International</em>. https://doi.org/10.1155/2016/6901286

Vancouver

Arutyunyan IV, Elchaninov A, Макаров ��, Fatkhudinov T. Umbilical Cord as Prospective Source for Mesenchymal Stem Cell‐Based Therapy. Stem Cells International. 2016. doi:10.1155/2016/6901286.

BibTeX

@article{i2016Umbili, title = {Umbilical Cord as Prospective Source for Mesenchymal Stem Cell‐Based Therapy}, author = {I. V. Arutyunyan and Andrey Elchaninov and А. В. Макаров and Timur Fatkhudinov}, journal = {Stem Cells International}, year = {2016}, doi = {10.1155/2016/6901286}, }