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The oncometabolite 2-hydroxyglutarate inhibits microglial activation via the AMPK/mTOR/NF-κB pathway

Chaojun Han, Jiyue Zheng, Lin Sun, Huicui Yang, Zhongqiang Cao, Xiaohu Zhang, Long Tai Zheng, Xue-chu Zhen

Acta Pharmacologica Sinica · 2019 · ▲ 66 citations

Deregulated nutrient-sensing

Abstract

This study in Acta Pharmacologica Sinica (2019) examines the role of 2-hydroxyglutarate in regulating microglial activation through the AMPK/mTOR/NF-kB pathway.

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Provenance

Source: OpenAlex
DOI: 10.1038/s41401-019-0225-9
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Fetched: 2026-06-21 MST

Cite this

APA

Han, C., Zheng, J., Sun, L., Yang, H., Cao, Z., Zhang, X., Zheng, L.T., & Zhen, X. (2019). The oncometabolite 2-hydroxyglutarate inhibits microglial activation via the AMPK/mTOR/NF-κB pathway. <em>Acta Pharmacologica Sinica</em>. https://doi.org/10.1038/s41401-019-0225-9

Vancouver

Han C, Zheng J, Sun L, Yang H, Cao Z, Zhang X, et al. The oncometabolite 2-hydroxyglutarate inhibits microglial activation via the AMPK/mTOR/NF-κB pathway. Acta Pharmacologica Sinica. 2019. doi:10.1038/s41401-019-0225-9.

BibTeX

@unpublished{chaojun2019Theonc, title = {The oncometabolite 2-hydroxyglutarate inhibits microglial activation via the AMPK/mTOR/NF-κB pathway}, author = {Chaojun Han and Jiyue Zheng and Lin Sun and Huicui Yang and Zhongqiang Cao and Xiaohu Zhang and Long Tai Zheng and Xue-chu Zhen}, journal = {Acta Pharmacologica Sinica}, year = {2019}, doi = {10.1038/s41401-019-0225-9}, }