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The Ensembl Variant Effect Predictor

William McLaren, Laurent Gil, Sarah Hunt, Harpreet Singh Riat, Graham R. S. Ritchie, Anja Thormann, Paul Flicek, Fiona Cunningham

Genome biology · 2016 · ▲ 8,831 citations

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Abstract

The Ensembl Variant Effect Predictor is a powerful toolset for the analysis, annotation, and prioritization of genomic variants in coding and non-coding regions. It provides access to an extensive collection of genomic annotation, with a variety of interfaces to suit different requirements, and simple options for configuring and extending analysis. It is open source, free to use, and supports full reproducibility of results. The Ensembl Variant Effect Predictor can simplify and accelerate variant interpretation in a wide range of study designs.

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Provenance

Source: OpenAlex
DOI: 10.1186/s13059-016-0974-4
Canonical: link ↗
Fetched: 2026-07-26 MST

Cite this

APA

McLaren, W., Gil, L., Hunt, S., Riat, H.S., Ritchie, G.R.S., Thormann, A., Flicek, P., & Cunningham, F. (2016). The Ensembl Variant Effect Predictor. <em>Genome biology</em>. https://doi.org/10.1186/s13059-016-0974-4

Vancouver

McLaren W, Gil L, Hunt S, Riat HS, Ritchie GRS, Thormann A, et al. The Ensembl Variant Effect Predictor. Genome biology. 2016. doi:10.1186/s13059-016-0974-4.

BibTeX

@article{william2016TheEns, title = {The Ensembl Variant Effect Predictor}, author = {William McLaren and Laurent Gil and Sarah Hunt and Harpreet Singh Riat and Graham R. S. Ritchie and Anja Thormann and Paul Flicek and Fiona Cunningham}, journal = {Genome biology}, year = {2016}, doi = {10.1186/s13059-016-0974-4}, }