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Tearful relations: oxidative stress, inflammation and eye diseases

Tais Hitomi Wakamatsu, Murat Doğru, Kazuo Tsubota

Arquivos Brasileiros de Oftalmologia · 2008 · ▲ 155 citations

Mitochondrial dysfunction Chronic inflammation Review

Abstract

Oxidative stress is caused by an imbalance between the production of reactive oxygen species and ability the biological systems' defense mechanisms necessary to eliminate the stress. It has been accepted that oxidative stress is involved in many acute and chronic diseases and even in normal aging. Recently, increased awareness of oxidative stress damage and its relation with ocular surface diseases incite researchers to discover possible mechanisms in the development of dry eye disease. This review focuses on the evaluation of the influence of oxidative stress on eye diseases emphasizing its relation with the pathogenesis of dry eye disease.

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Provenance

Source: OpenAlex
DOI: 10.1590/s0004-27492008000700015
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Fetched: 2026-10-21 MST

Cite this

APA

Wakamatsu, T.H., Doğru, M., & Tsubota, K. (2008). Tearful relations: oxidative stress, inflammation and eye diseases. <em>Arquivos Brasileiros de Oftalmologia</em>. https://doi.org/10.1590/s0004-27492008000700015

Vancouver

Wakamatsu TH, Doğru M, Tsubota K. Tearful relations: oxidative stress, inflammation and eye diseases. Arquivos Brasileiros de Oftalmologia. 2008. doi:10.1590/s0004-27492008000700015.

BibTeX

@article{tais2008Tearfu, title = {Tearful relations: oxidative stress, inflammation and eye diseases}, author = {Tais Hitomi Wakamatsu and Murat Doğru and Kazuo Tsubota}, journal = {Arquivos Brasileiros de Oftalmologia}, year = {2008}, doi = {10.1590/s0004-27492008000700015}, }