Open access · US-GOV via ClinicalTrials.gov Clinical trial

Targeting Intramuscular Adipose Quality in Aging

Authors not listed

Washington University School of Medicine · 2026

Altered intercellular communication Chronic inflammation Exercise Human Randomized controlled trial

Abstract

This study will test the central hypothesis that fat within the muscle, or intramuscular adipose tissue (IMAT), exhibits elevated damage and pro-inflammatory signaling with aging, both of which are reduced by progressive resistance exercise (PRE). Sixteen older adults 65-80 years old will be recruited and complete a 12 week calf PRE intervention. Calf muscle strength, composition (measured by computed tomography) and muscle biopsies will be collected before and after the intervention. Histology, transcriptomic and secretomic tests will be completed to assess signs of damage and inflammation.

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Provenance

Source: ClinicalTrials.gov
Canonical: link ↗
Fetched: 2026-07-02 MST

Cite this

APA

Anonymous. (2026). Targeting Intramuscular Adipose Quality in Aging. <em>Washington University School of Medicine</em>. https://clinicaltrials.gov/study/NCT07506681

Vancouver

Anonymous. Targeting Intramuscular Adipose Quality in Aging. Washington University School of Medicine. 2026.

BibTeX

@misc{anon2026Target, title = {Targeting Intramuscular Adipose Quality in Aging}, author = {Anonymous}, journal = {Washington University School of Medicine}, year = {2026}, }