Open access · CC-BY via OpenAlex

Relationships of depression and antidepressant use with epigenetic age acceleration and all-cause mortality among postmenopausal women

May A. Beydoun, Hind A. Beydoun, Jason J. Ashe, Michael F. Georgescu, Steve Horvath, Ake Tzu-Hui Lu, Anthony S. Zannas, Aladdin H. Shadyab, Su Yon Jung, Sylvia W Wassertheil-Smoller, Ramon Casanova, Alan B. Zonderman, Robert L. Brunner

Aging · 2024 · ▲ 6 citations

Epigenetic alterations

＋ Sign in to save

Abstract

< 0.05). Thus, higher AgeAccelGrim partially explained the relationship between antidepressant use and increased all-cause mortality risk, though only prior to controlling for lifestyle and health-related factors. Antidepressant use and epigenetic age acceleration independently predicted increased all-cause mortality risk. Further studies are needed in varying populations.

◌ CITATION ONLY
Full text is not openly licensed for redistribution here. Read it at the source:

Read at source →

Provenance

Source: OpenAlex
DOI: 10.18632/aging.205868
Canonical: link ↗
Fetched: 2026-10-16 MST

Cite this

APA

Beydoun, M.A., Beydoun, H.A., Ashe, J.J., Georgescu, M.F., Horvath, S., Lu, A.T., Zannas, A.S., Shadyab, A.H., Jung, S.Y., Wassertheil-Smoller, S.W., Casanova, R., Zonderman, A.B., & Brunner, R.L. (2024). Relationships of depression and antidepressant use with epigenetic age acceleration and all-cause mortality among postmenopausal women. <em>Aging</em>. https://doi.org/10.18632/aging.205868

Vancouver

Beydoun MA, Beydoun HA, Ashe JJ, Georgescu MF, Horvath S, Lu AT, et al. Relationships of depression and antidepressant use with epigenetic age acceleration and all-cause mortality among postmenopausal women. Aging. 2024. doi:10.18632/aging.205868.

BibTeX

@article{may2024Relati, title = {Relationships of depression and antidepressant use with epigenetic age acceleration and all-cause mortality among postmenopausal women}, author = {May A. Beydoun and Hind A. Beydoun and Jason J. Ashe and Michael F. Georgescu and Steve Horvath and Ake Tzu-Hui Lu and Anthony S. Zannas and Aladdin H. Shadyab and Su Yon Jung and Sylvia W Wassertheil-Smoller and Ramon Casanova and Alan B. Zonderman and Robert L. Brunner}, journal = {Aging}, year = {2024}, doi = {10.18632/aging.205868}, }