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Mitochondrial dysfunction and ovarian aging

Tianren Wang, Man Zhang, Zongliang Jiang, Emre Seli

American Journal of Reproductive Immunology · 2017 · ▲ 115 citations

Mitochondrial dysfunction Cellular senescence

Abstract

Mitochondria are double-membrane-bound organelles that are responsible for the generation of most of the cell's energy. Mitochondrial dysfunction has been implicated in cellular senescence in general and ovarian aging in particular. Recent studies exploited this association by studying mitochondrial DNA (mtDNA) copy number as a potential biomarker of embryo viability and the use of mitochondrial nutrients and autologous mitochondrial transfer as a potential treatment for poor ovarian function and response.

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Provenance

Source: OpenAlex
DOI: 10.1111/aji.12651
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Fetched: 2026-08-19 MST

Cite this

APA

Wang, T., Zhang, M., Jiang, Z., & Seli, E. (2017). Mitochondrial dysfunction and ovarian aging. <em>American Journal of Reproductive Immunology</em>. https://doi.org/10.1111/aji.12651

Vancouver

Wang T, Zhang M, Jiang Z, Seli E. Mitochondrial dysfunction and ovarian aging. American Journal of Reproductive Immunology. 2017. doi:10.1111/aji.12651.

BibTeX

@article{tianren2017Mitoch, title = {Mitochondrial dysfunction and ovarian aging}, author = {Tianren Wang and Man Zhang and Zongliang Jiang and Emre Seli}, journal = {American Journal of Reproductive Immunology}, year = {2017}, doi = {10.1111/aji.12651}, }