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Lung Cancer

Roy S. Herbst, John V. Heymach, Scott M. Lippman

New England Journal of Medicine · 2008 · ▲ 2,389 citations

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Abstract

The Molecular Origins of Cancer series continues with this review of molecular and genetic mechanisms of lung cancer. The authors review genetic susceptibility to lung cancer and four genes of importance in the evolution of the disease: EGFR, KRAS, the PI3K–Akt–mTOR complex, and TITF1. They also discuss gene profiling and protein profiling, with emphasis on the clinical value of these methods.

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Provenance

Source: OpenAlex
DOI: 10.1056/nejmra0802714
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Fetched: 2026-06-05 MST

Cite this

APA

Herbst, R.S., Heymach, J.V., & Lippman, S.M. (2008). Lung Cancer. <em>New England Journal of Medicine</em>. https://doi.org/10.1056/nejmra0802714

Vancouver

Herbst RS, Heymach JV, Lippman SM. Lung Cancer. New England Journal of Medicine. 2008. doi:10.1056/nejmra0802714.

BibTeX

@unpublished{roy2008LungCa, title = {Lung Cancer}, author = {Roy S. Herbst and John V. Heymach and Scott M. Lippman}, journal = {New England Journal of Medicine}, year = {2008}, doi = {10.1056/nejmra0802714}, }