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Induced pluripotent stem cells in hematology: current and future applications

Daniele Focosi, Giovanni Amabile, Annalisa Di Ruscio, Paola Quaranta, Daniel G. Tenen, Mauro Pistello

Blood Cancer Journal · 2014 · ▲ 23 citations

Stem-cell exhaustion Partial reprogramming (OSK) Human Review

Abstract

Reprogramming somatic cells into induced pluripotent stem (iPS) cells is nowadays approaching effectiveness and clinical grade. Potential uses of this technology include predictive toxicology, drug screening, pathogenetic studies and transplantation. Here, we review the basis of current iPS cell technology and potential applications in hematology, ranging from disease modeling of congenital and acquired hemopathies to hematopoietic stem and other blood cell transplantation.

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Provenance

Source: OpenAlex
DOI: 10.1038/bcj.2014.30
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Fetched: 2026-06-19 MST

Cite this

APA

Focosi, D., Amabile, G., Ruscio, A.D., Quaranta, P., Tenen, D.G., & Pistello, M. (2014). Induced pluripotent stem cells in hematology: current and future applications. <em>Blood Cancer Journal</em>. https://doi.org/10.1038/bcj.2014.30

Vancouver

Focosi D, Amabile G, Ruscio AD, Quaranta P, Tenen DG, Pistello M. Induced pluripotent stem cells in hematology: current and future applications. Blood Cancer Journal. 2014. doi:10.1038/bcj.2014.30.

BibTeX

@article{daniele2014Induce, title = {Induced pluripotent stem cells in hematology: current and future applications}, author = {Daniele Focosi and Giovanni Amabile and Annalisa Di Ruscio and Paola Quaranta and Daniel G. Tenen and Mauro Pistello}, journal = {Blood Cancer Journal}, year = {2014}, doi = {10.1038/bcj.2014.30}, }