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Increased post-mitotic senescence in aged human neurons is a pathological feature of Alzheimer’s disease

Joseph R. Herdy, Larissa Traxler, Ravi Kant Agrawal, Lukas Karbacher, Johannes C. M. Schlachetzki, Lena Boehnke, Dina Zangwill, Doug Galasko, Christopher K. Glass, Jérôme Mertens, Fred H. Gage

Cell stem cell · 2022 · ▲ 199 citations

Cellular senescence Human

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Abstract

This 2022 study in Cell stem cell examines increased post-mitotic senescence in aged human neurons as a pathological feature of Alzheimer disease.

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Provenance

Source: OpenAlex
DOI: 10.1016/j.stem.2022.11.010
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Fetched: 2026-08-02 MST

Cite this

APA

Herdy, J.R., Traxler, L., Agrawal, R.K., Karbacher, L., Schlachetzki, J.C.M., Boehnke, L., Zangwill, D., Galasko, D., Glass, C.K., Mertens, J., & Gage, F.H. (2022). Increased post-mitotic senescence in aged human neurons is a pathological feature of Alzheimer’s disease. <em>Cell stem cell</em>. https://doi.org/10.1016/j.stem.2022.11.010

Vancouver

Herdy JR, Traxler L, Agrawal RK, Karbacher L, Schlachetzki JCM, Boehnke L, et al. Increased post-mitotic senescence in aged human neurons is a pathological feature of Alzheimer’s disease. Cell stem cell. 2022. doi:10.1016/j.stem.2022.11.010.

BibTeX

@unpublished{joseph2022Increa, title = {Increased post-mitotic senescence in aged human neurons is a pathological feature of Alzheimer’s disease}, author = {Joseph R. Herdy and Larissa Traxler and Ravi Kant Agrawal and Lukas Karbacher and Johannes C. M. Schlachetzki and Lena Boehnke and Dina Zangwill and Doug Galasko and Christopher K. Glass and Jérôme Mertens and Fred H. Gage}, journal = {Cell stem cell}, year = {2022}, doi = {10.1016/j.stem.2022.11.010}, }