Citation only via OpenAlex

Failure to find the a‐synuclein gene missense mutation (G 209 A) in 100 patients with younger onset Parkinson's disease

Piu Chan, Caroline M. Tanner, Xin Mei Jiang, J. William Langston

Neurology · 1998 · ▲ 93 citations

Loss of proteostasis Human

Abstract

The missense G209A mutation at exon 4 of the alpha-synuclein gene was recently found to be responsible for familial Parkinson's disease (PD) in a large kindred of Italian descent. We studied 100 typical PD patients with onset before age 51, both with and without a family history of PD. We did not find this alpha-synuclein missense mutation in any patient, but it was present in a symptomatic member of the Contursi family.

◌ CITATION ONLY
Full text is not openly licensed for redistribution here. Read it at the source:

Read at source →

Provenance

Source: OpenAlex
DOI: 10.1212/wnl.50.2.513
Canonical: link ↗
Fetched: 2026-10-20 MST

Cite this

APA

Chan, P., Tanner, C.M., Jiang, X.M., & Langston, J.W. (1998). Failure to find the a‐synuclein gene missense mutation (G 209 A) in 100 patients with younger onset Parkinson's disease. <em>Neurology</em>. https://doi.org/10.1212/wnl.50.2.513

Vancouver

Chan P, Tanner CM, Jiang XM, Langston JW. Failure to find the a‐synuclein gene missense mutation (G 209 A) in 100 patients with younger onset Parkinson's disease. Neurology. 1998. doi:10.1212/wnl.50.2.513.

BibTeX

@article{piu1998Failur, title = {Failure to find the a‐synuclein gene missense mutation (G 209 A) in 100 patients with younger onset Parkinson's disease}, author = {Piu Chan and Caroline M. Tanner and Xin Mei Jiang and J. William Langston}, journal = {Neurology}, year = {1998}, doi = {10.1212/wnl.50.2.513}, }