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Extracellular vesicles tell all: How vesicle-mediated cellular communication shapes hematopoietic stem cell biology with increasing age

Isabelle Grenier‐Pleau, Sheela A. Abraham

Experimental Hematology · 2021 · ▲ 12 citations

Stem-cell exhaustion Altered intercellular communication Review

Abstract

Extracellular vesicles (EVs) are small lipid bilayer particles containing biologically important cargo and impart regulatory changes in target cells. Despite the importance of EVs in cellular communication, there remains a gap in our understanding of how EVs influence HSC fate and, in turn, how aging and longevity are affected. This review summarizes the current literature dealing with how age-altered intercellular communication mediated by EVs influences HSC biology.

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Provenance

Source: OpenAlex
DOI: 10.1016/j.exphem.2021.08.004
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Fetched: 2026-06-08 MST

Cite this

APA

Grenier‐Pleau, I., & Abraham, S.A. (2021). Extracellular vesicles tell all: How vesicle-mediated cellular communication shapes hematopoietic stem cell biology with increasing age. <em>Experimental Hematology</em>. https://doi.org/10.1016/j.exphem.2021.08.004

Vancouver

Grenier‐Pleau I, Abraham SA. Extracellular vesicles tell all: How vesicle-mediated cellular communication shapes hematopoietic stem cell biology with increasing age. Experimental Hematology. 2021. doi:10.1016/j.exphem.2021.08.004.

BibTeX

@article{isabelle2021Extrac, title = {Extracellular vesicles tell all: How vesicle-mediated cellular communication shapes hematopoietic stem cell biology with increasing age}, author = {Isabelle Grenier‐Pleau and Sheela A. Abraham}, journal = {Experimental Hematology}, year = {2021}, doi = {10.1016/j.exphem.2021.08.004}, }